• Anastasia Christianson on Pfizer’s Approach to AI, ML, and the Digital Age

    Bio-IT World | At Pfizer, AI plays a key role in every step of the drug discovery process, Anastasia Christianson, Global Head of AI, ML, Analytics, and Data at Pfizer, tells Bio-Team co-founder Stan Gloss on the latest episode of the Trends from the Trenches podcast. Christianson will be the opening keynote at the 2023 Bio-IT World Conference & Expo, May 16-18, 2023, in Boston.

    May 4, 2023

  • Novel Mouse Avatars Could Advance Personalized Medicine For Cancer

    Bio-IT World | Up to now, mouse avatars haven’t proven to be particularly good tools for forecasting treatment response in human cancer patients. But new models being generated by an international team of researchers are expected to be far more predictive of what is going to happen with different cohorts of clinical trial participants.

    May 3, 2023

  • Oxford Nanopore Targets Diagnostics, New Products from Vizgen, Agilent, More

    Bio-IT World | Ginkgo Bioworks acquires an adeno-associated virus capsid discovery and engineering platform; Oxford Nanopore Technologies and bioMérieux SA have teamed up bring nanopore sequencing to the infectious disease diagnostics market, and the emergency of Large Language Models ops. Plus, new products from Metabolon, Cytiva, Vizgen, Agilent, and more.

    Apr 27, 2023

  • PEACE Study Offers New Clues About How Cancer Resists Treatment

    Bio-IT World | Research autopsies are nothing new—the use of post-mortem tissues for cancer research has been ongoing since the end of the nineteenth century—but the Cancer Research UK-sponsored PEACE (posthumous evaluation of advanced cancer environment) study stands apart by virtue of its scope and scale. The pan-cancer initiative intends to enroll 500 patients across the country in hopes of understanding cancer evolution, drug resistance and why patients die of their disease.

    Apr 26, 2023

  • Follow the Money: Multi-omic Drug Discovery, Antibody Manufacturing, Biopolar Focus, More

    Bio-IT World | Big money for small-batch antibodies, investment in understanding bipolar disorder, Mercy BioAnalytics nets Series A for detecting cancer biomarkers on the surface of tumor-derived extracellular vesicles; and more.

    Apr 25, 2023

  • Embracing Automation to Integrate Medical Information and Safety Operations

    Bio-IT World | Businesses depend on data to inform strategy and measure success across all industries. To benefit from automated workflows, life sciences organizations must integrate disparate systems. End-to-end, open architecture solutions facilitate communication between multiple platforms with minimal friction or tedious, time-consuming middle steps.

    Apr 21, 2023

  • Bio-IT World Names 2023 Innovative Practices Winners

    Bio-IT World| Bio-IT World today announced the 2023 Innovative Practices Awards winners. Six projects were honored. Companies involved in the winning entries included AbbVie, Bayer G4A; Carenostics; City of Hope; Generate Biomedicines; Hackensack Meridian Health; Higher Steaks; Regeneron Pharmaceuticals; SciBite; and Synthace.

    Apr 19, 2023

  • Deep Proteome Sequencing Answers Longstanding Biology Question

    Bio-IT World | Debate about whether RNA splicing events code for different proteins may finally be over, thanks to international research efforts and a new sequencing method that enumerates the massive number of human protein alterations in standard proteomics experiments.

    Apr 18, 2023

  • NVIDIA and Mitsui Launch Japan’s First Generative AI Supercomputer to Accelerate Drug Discovery

    Bio-IT World | In collaboration with NVIDIA, Mitsui, Japan, recently launched Tokyo-1, a supercomputer designed to boost Japan’s $100B pharmaceutical industry. The project features 16 NVIDIA DGX H100 AI systems—a part of NVIDIA’s NGX enterprise AI platform—to simulate high-resolution molecular dynamics and generate AI models for accelerated drug discovery.

    Apr 14, 2023

  • Protein-Metabolite Interactome Is Vast Untapped Frontier For Drug Discovery

    Bio-IT World | Researchers at the University of Utah have created a systematic approach to reveal the endogenous protein-metabolite interactome at high-throughput speed. The platform quickly identifies metabolites that putatively interact with target proteins.

    Apr 13, 2023

  • AI-Based Retinal Aging Clock Gauges Effectiveness Of Anti-Aging Interventions

    Bio-IT World | Retinal scans offer a fascinating window into the health of the body’s circulatory system and brain functioning as well as identify eye diseases that aren't visibly noticeable. Now, a new study suggests that this artificial intelligence-based technology is also good for predicting how well people are aging.

    Apr 11, 2023

  • For Success in Lab Automation, Bridge the Gap Between Science and IT

    Bio-IT World | When implementing laboratory automation, one of the biggest challenges can be group dynamics: getting scientific and IT teams on the same page. Both groups are integral to the success of an automated setup, but often they have very different perspectives and might even be resistant to working together. It’s important to understand why so that we can overcome this issue.

    Apr 7, 2023

  • Global Collaboration Enables Headway On Rare Neuroendocrine Tumors

    Bio-IT World | Researchers in Madrid recently wrapped up the largest-yet genomic study of rare neuroendocrine tumors, known as pheochromocytomas and paragangliomas, which identified a seemingly perfect panel of metastatic disease markers as well as a group of patients who could potentially benefit from immunotherapy. The objective here is a better means to predict, at the time of diagnosis of the primary tumor, whether patients will be immediately affected by cancer spread.

    Apr 6, 2023

  • ‘AMAR’ Is Latest Addition To The List Of Anti-Aging Hopefuls

    Bio-IT World | Using “genetic trickery,” scientists at the University of Virginia (UVA) have hit on a means to detoxify the body of fat byproducts and, with that, extend the healthy lifespan of the model organism C. Elegans. The specific trick was to boost the activity of two enzymes involved in alcohol detoxification.

    Apr 4, 2023

  • Johns Hopkins, NASA to Send Human Heart ‘Tissue-on-a-Chip’ Into Space, New Adverse Event Detection Product Aids Pharmacovigilance Surveillance, More

    Bio-IT World | A proprietary deep learning platform that identifies novel molecules through protein-ligand co-folding; PacBio’s long-read sequencing systems help researchers scale their interrogation of the full genome; a cardiovascular disease detection platform that combines the latest advancements in applied machine learning with one of the most ubiquitous medical devices in the world: the stethoscope; and more.

    Mar 30, 2023

  • Illumina Releases International Version of Tertiary Clinical NGS Analysis Software

    Bio-IT World | Illumina has released Connected Insights, a cloud-based software for tertiary analysis for clinical next-generation sequencing (NGS) data. The software is commercially available in a limited number of countries and in beta testing in the US.

    Mar 29, 2023

  • Genome Citation Service Tracks Genomes Across Research

    Bio-IT World | Kjiersten Fagnan, chief informatics officer at Lawrence Berkeley National Laboratory’s Joint Genome Institute appears on the Trends from the Trenches podcast to speak with host Stan Gloss of BioTeam about the JGI’s Genome Citation Service, a new offering that connects the broader community with the organization’s data resources and infrastructure.

    Mar 28, 2023

  • Follow the Money: Recombinase Platform Unlocks Full Potential of Gene Editing, Lead Drug Candidate Clears Neurodegenerative Toxins, More

    Bio-IT World | Funding pipeline advancement of first-in-class extracellular protein degraders, a proteomics AI-based platform that comprehensively maps the course of a disease, a proprietary computational antibody drug discovery platform that uses machine learning to model antibody-antigen interactions, and more.

    Mar 28, 2023

  • PacBio Releases Computational Tool for Parsing Pseudogenes

    Bio-IT World | PacBio last week announced a new informatics method that genotypes gene paralogs and pseudogenes with high accuracy. The computational tool, named Paraphase, enables variant calling, copy number analysis and phasing by identifying the full gene sequence of each of the haplotypes for all genes and pseudogenes of the same gene family.

    Mar 24, 2023

  • Neighborhood Analysis Highlights Role Of Macrophages In ER+ Breast Cancers

    Bio-IT World | When it comes to breast cancer, the most commonly occurring estrogen receptor-positive (ER+) variety is a poor candidate for treatment with conventional immunotherapies designed to help the patient’s own immune system fight back. Unlike triple-negative breast cancer, ER+ tumors don’t have many infiltrating T cells so potentiating their function alone doesn’t make much of a difference.

    Mar 22, 2023