• Molecule Takes On Deadly Cancer By Inhibiting ‘Unfolded Protein Response’

    Bio-IT World | Researchers in a joint European network report on a specially developed molecule known as Z4P that could deliver fresh hope to patients with glioblastoma, the most aggressive malignant primary brain tumor with a less than 7% survival rate five years post-diagnosis. As an adjunct to gold-standard chemotherapy, Z4P effectively inhibits the stress management pathway of cancer cells so they self-destruct.

    Jun 22, 2023

  • Platform and Projects: Genomics England’s New Efforts

    Bio-IT World | At the Bio-IT World Conference & Expo last month, members of the Genomics England team shared about the organization’s history, vision, and what it’s working on now.

    Jun 21, 2023

  • Revolutionizing Lab Work: How Automation Empowers Lab Technicians and Scientists and Reduces Manual Workload

    Bio-IT World | As the life sciences industry continues to grow and innovate, it is critical for labs to leverage automation technology to reduce manual workload and unlock new avenues for scientific discovery. With breakthroughs in gene-editing, increased healthcare testing, and genomic surveillance due to the COVID-19 pandemic, labs cannot afford to have highly qualified scientists tied to their benches performing easily automatable tasks.

    Jun 16, 2023

  • N-Lorem Foundation Bringing Real Hope To ‘N-Of-1’ Patients

    Bio-IT World | Stanley T. Crooke, M.D., Ph.D., founder and longtime leader of the company that pioneered RNA-targeted therapeutics, is now chairman and CEO of the n-Lorem Foundation descaling the technology to treat patients helpless before a healthcare system that wasn’t built for “n-of-1” problems. He will be addressing a room of physicians and scientists tomorrow on the campus of Vanderbilt University.

    Jun 14, 2023

  • Science Diplomats Sound the Alarm for Resiliency Preparedness at BIO Convention

    Bio-IT World | BOSTON—The largest biotechnology conference in the world, the BIO International Conference, convened in Boston this week drawing over 20,000 attendees from more than 60 countries. In our post-pandemic world, the common thread throughout the conference was the need for global collaboration on our scientific challenges.

    Jun 13, 2023

  • Illumina CEO Resigns

    Bio-IT World | Illumina announced yesterday that Francis deSouza, Illumina's Chief Executive Officer and a Director, has resigned, effective Sunday, June 11.

    Jun 12, 2023

  • Capsule-Sized Device Permits Noninvasive Exploration Of Small Intestine

    Bio-IT World | An international team of researchers has completed preliminary testing of a swallowable device for collecting samples from people under standard, day-to-day conditions to better understand what is happening inside their small intestine. The lengthy organ has up to how been inaccessible unless individuals first fasted and were sedated.

    Jun 8, 2023

  • Data-Generating AI Platform Conducts Huge Number Of Microbial Experiments

    Bio-IT World | Bioengineers at the University of Michigan (U-M) have seriously scaled up data collection on bacterial species known to affect human health with robots and an artificial intelligence (AI) system that learns from scratch without the need for big databases of knowledge to train on. Dubbed BacterAI, the platform generates its own data and quickly gets smarter by playing a game doling out reward points for accurately predicting the outcome of an experiment.

    Jun 7, 2023

  • Nature-Inspired Orthopedic Implant Coating Kills Bacteria, Monitors Strain

    Bio-IT World | Researchers at the University of Illinois Urbana-Champaign believe they have come up with an attractive approach to the battle against bacteria that can infect orthopedic implants—as well as the surfaces people encounter in everyday life, smartphone screens and kitchen countertops. The smart surgical implant coating contains no chemicals but was instead inspired by the wings of cicadas and dragonflies that are naturally antibacterial through physical interactions.

    Jun 6, 2023

  • ‘The Process Is the Product’ Is No Longer Enough. Now, Data Is the Deliverable

    Bio-IT World | In biomanufacturing, particularly with respect to advanced therapies such as gene and cell therapies, there is a saying: "the process is the product." That insight is still important, but it's also insufficient. As the industry adapts to increasingly complex manufacturing processes, we'd like to propose a reframe: the data is the deliverable. For personalized medicine to reach its potential, leveraging process data to drive learning will be key.

    Jun 1, 2023

  • Follow the Money: Cell Therapy, Genetic Research, Protein-Protein Interactions, More

    Bio-IT World | ElevateBio takes top funding award for Series D round for cell and gene therapy platform; NIH funds research on somatic mosaicism, engineered cell therapy; DOD funds the gathering of more protein-protein interaction data; more.

    May 30, 2023

  • DNA Printing, Bioengineered Kidney Constructs in Space, Revvity’s Big Pharma Agreements, More

    Bio-IT World | The Association for Molecular Pathology releases recommendations for germline variants detected by NGS, 10x Genomics wins German injunction against NanoString Technologies, and Revvity—formerly PerkinElmer—announces new license agreement with AstraZeneca. Plus new products and deployments from DNA Script, Thermo Fisher, Model N, GenScript, and more.

    May 24, 2023

  • Bryn Roberts on Data Citizenship, FAIR Culture, Data Models for the Long Term

    Bio-IT World | Bryn Roberts has spent thirty years in informatics and data, most recently at Roche and before that at AstraZeneca. Now as Global Head of Data and Analytics at Roche Information Solutions, Roberts applies his career-long learnings to the current era of data in life sciences.

    May 23, 2023

  • Bio-IT World Community Names Five New ‘Best of Show’ Products

    Bio-IT World | Earlier this week during the Bio-IT World Conference & Expo, Bio-IT World named five 2023 Best of Show Awards winners including new products from Data Cicada, Genomenon, GitHub, Monomer Bio, and Starfish Storage.

    May 19, 2023

  • New Antimicrobial Susceptibility Test Suggests Generic Z-Pak Can Cure Superbugs

    Bio-IT World | A new antimicrobial susceptibility testing (AST) method developed by scientists at the University of California, Santa Barbara, resolves the longstanding conflict between what the gold-standard assay says will work and actual patient outcomes when it comes to selecting antibiotics. The alternative AST protocol reveals that antibiotics already widely available on the market can cure superbugs.

    May 18, 2023

  • Variation In The Gut Highlights Human Individuality

    Bio-IT World | Anatomical investigations performed on 45 individuals who donated their bodies to science have revealed that the human gut is stunningly diverse based on the size of the organs making up the gastrointestinal (GI) system. Whether those differences are based on what people eat, where they live, or their ancestry is anyone’s guess.

    May 16, 2023

  • Illumina Relaunches Correlation Engine, Banking on Need for ‘Omics Informatics Tools

    Bio-IT World | Illumina is relaunching its BaseSpace Correlation Engine—now simply Illumina Correlation Engine—as the sequencing company emphasizes connecting its informatics components together, Mike LeliveIt, VP of Product Management, told Bio-IT World. “What people want now is for the components to talk to each other so they can get work done and they don’t have to build tools. Our shift to Illumina Connected Software really represents the importance of what we’re building.”

    May 11, 2023

  • Novel Wound Dressing Monitors For Infection In Real Time

    Bio-IT World | Researchers in Sweden who previously introduced a hydrogel wound dressing constructed of nanocellulose that requires no changing have further improved on their innovation with the integration of a pH sensor to passively monitor for early signs of infection. In parallel, they’re working on antimicrobial substances based on lipopeptides that are showing potency against multiple types of bacteria.

    May 10, 2023

  • Bio-IT World Announces Best of Show Finalists, People’s Choice Contenders

    Bio-IT World | Bio-IT World announced the companies contending the for 2023 Best of Show Awards today. Thirty-three new products will be exhibited on the floor for attendees to view at the Bio-IT World Conference & Expo, May 16-18, at the Hynes Convention Center in Boston.

    May 9, 2023

  • Accelerating Implementation: Unlocking the Potential of Next-Generation Sequencing

    Bio-IT World | Next-generation sequencing (NGS) has revolutionized molecular biology and served as a universal tool for many research avenues across the spectrum of biology. With the NGS market expanding, three key barriers—time, cost, and expertise—are holding back the potential of NGS and the full impact it could have on society, diagnostics, and precision medicine.

    May 5, 2023