• Follow the Money: Lymphatic System Platform, Endovascular Device System, Generative AI For Small Molecule Therapies, More

    Bio-IT World | Seaport Therapeutics plans to advance their Glyph platform, which leverages the lymphatic system to create new medicines building on clinically validated mechanisms and has demonstrated clinical proof-of-concept; Nectero Medical will accelerate the execution of the Phase II/III (stAAAble) trial and to support the submission of a New Drug Application with the U.S. Food and Drug Administration for the Nectero Endovascular Aneurysm Stabilization Treatment (Nectero EAST) System; DeepCure will further develop its generative AI and physics-based engine to innovate the discovery of small molecule therapies for challenging targets; more.

    Apr 24, 2024

  • AI Ushers in HPC Revival Says TACC’s Dan Stanzione

    Bio-IT World | High performance computing is enjoying an extreme vindication, said Dan Stanzione, Associate Vice President for Research at The University of Texas at Austin and Executive Director of TACC. In the opening plenary presentation at last week’s Bio-IT World Conference & Expo, Stanzione said that after years of cloud computing hype, artificial intelligence now demands traditional high performance computing architecture.

    Apr 23, 2024

  • Unlocking Targeted Cancer Care: Biomarkers as the Key to Personalized Treatments

    Bio-IT World | In modern medicine, biomarkers stand as pivotal indicators of biological processes or responses to therapeutic interventions, signaling a new era in clinical trial design and patient care. The driving idea behind the use of these tools is that by integrating the right biomarker information, scientists can properly select patients who are most likely to benefit from a particular therapy.

    Apr 19, 2024

  • New Products Win Praise at 2024 Bio-IT World Best of Show Awards

    Bio-IT World | Bio-IT World announced six Best of Show winners yesterday at the 2024 Bio-IT World Conference & Expo in Boston. Honored new products came from winning companies including Combinatics, Osprey, Maxis.IT, Nurocore, Velsera, and Xybion.

    Apr 16, 2024

  • Age of Opportunity: Artificial Intelligence and the Precision Medicine Future

    Bio-IT World | At the Precision Med TriConference 2024, Illumina Ventures partner Mara Aspinall sat with Eric Topol, endowed chair and executive VP and professor at Scripps Translational Science Institute, in a fireside chat to discuss precision medicine and artificial intelligence (AI). With three published books and more than 1,200 peer reviewed publications, Topol is one of the industry’s leading minds on digital medicine, and from his perspective, AI needs to be adapted sooner.

    Apr 16, 2024

  • Effects Of Genetic Mutations Become Knowable With ‘Super Minigene’ System

    Bio-IT World | Molecular biologists at Iowa State University report the potential for the effects of genetic mutations to be known using a “super minigene” system developed in the lab of Ravindra Singh, Ph.D., professor of biomedical sciences.

    Apr 11, 2024

  • Novel Predictive Model For Explaining How Anti-Fibrotic Drugs Work

    Bio-IT World | In drug discovery, the focus of machine learning and artificial intelligence tools has been on predicting outcomes without explanation or understanding of the biochemical pathways mediating those effects. But rigorous translation requires a solid science-based foundation to explain how a drug works, not just that it does.

    Apr 10, 2024

  • NVIDIA GTC Panel Explores the Role of Generative AI in Medicine

    Bio-IT World | During the NVIDIA GTC conference held at the San Jose Convention Center and online March 18-21, NVIDIA CEO Jensen Huang highlighted an array of advancements, including new foundation models coming to NVIDIA BioNeMo, a collaboration with Johnson & Johnson MedTech to expand AI’s role in surgical settings, and the launch of over two dozen generative AI microservices to advance areas like digital health, medical technology, and drug discovery.

    Apr 9, 2024

  • Bio-IT World Names 2024 Best of Show Finalists, People’s Choice Contenders

    Bio-IT World | Bio-IT World announced the 2024 Best of Show Finalists and People’s Choice Contenders today, highlighting 26 new products from 27 different companies that will be on display at the Bio-IT World Conference and Expo, April 15-17, in Boston. The Best of Show Awards will honor several new products live at the event during the Best of Show Awards Reception beginning at 5:15 on Tuesday, April 16.

    Apr 8, 2024

  • Enhancing CRISPR: Utilizing Single-Cell Multiomics for CRISPR-based Drug Product Analysis

    Bio-IT World | The pace at which CRISPR has transitioned from a research tool to a therapeutic modality is remarkable. Initially targeting genetic diseases, CRISPR holds tremendous promise across various indications, rapidly expanding into oncology and infectious diseases, indicating CRISPR's vast and continual evolution as a modality.

    Apr 5, 2024

  • RNA-Protein Complex Contributing To ‘Background Autoimmunity’ In Women

    Bio-IT World | The single biggest risk factor for autoimmune disease is being biologically a female and many explanations have been proposed as to why that is, among them sex hormones and the X chromosome with its large number of immune-related genes.

    Apr 3, 2024

  • Spatial Biology: Market Outlook Across the Drug Discovery Pipeline

    Bio-IT World | Miguel Edwards, a partner at DeciBio Consulting, broke down the market outlook for spatial biology at last week’s Precision Medicine TriConference. “We think about this market really as opening up a new dimension of biological insight into tissue analysis,” Edwards said. “You’re seeing the excitement and promise for really improving our understanding of fundamental biology and really driving better therapeutics and better diagnostics.”

    Apr 2, 2024

  • Joseph La Barge On The Challenges Of Advancing Gene Therapy, Finding The Right Support

    Bio-IT World | In the newest episode of Trends from the Trenches, host Stan Gloss speaks with La Barge about his unique perspective on growing biotech businesses. La Barge delves into the challenges he and his team face in gene therapy advancement and how a company—especially one just starting out—can pave the path to successful research.

    Mar 28, 2024

  • PacBio’s Repeat Expansion Panel, Owkin-Sanofi AI Take on Immunology, More

    Bio-IT World | PacBio announced the PureTarget repeat expansion panel, a new solution designed to enable the comprehensive analysis of 20 genes associated with serious neurological disorders; Owkin and Sanofi take on immunology; new products from Beckman Coulter, Arrayjet, and PatientSight; and more.

    Mar 27, 2024

  • Follow the Money: In Vivo CAR-T Candidate Development, Modular T Cell Engagers, Wearable Tech, More

    Bio-IT World | Capstan Therapeutics is advancing CPTX2309, their lead in vivo chimeric antigen receptor T cell (CAR-T) candidate, to early clinical proof-of-concept in autoimmune disorders; Clasp is developing modular T cell engagers tailored to each patient’s immune system that are directed to common oncogenic driver mutations, resulting in off-the-shelf, antibody-like medicines that can specifically target a wide variety of hard-to-treat tumor types; Ultrahuman plan to further manufacture capacity and deepen research in the health tracking space; and more.

    Mar 26, 2024

  • #BioITExpo: Agenda Highlights for the 2024 Bio-IT World Conference & Expo

    Bio-IT World | With the Bio-IT World Conference & Expo less than a month away, we are busy marking our schedules and planning our week. This year the event shifts a day, starting on Monday, and offers six deep-dive full day symposia on topics including automation, quantum computing, knowledge graphs, and more.

    Mar 22, 2024

  • New Basement Membrane Extract Discovery Lifts Uncertainty For Clinical Trials

    Bio-IT World | But do different BME brands affect drug responses and gene expressions in organoids? To determine the answer, researchers at the Salk Institute tested out different BMEs to see their effects on pancreatic cancer organoids.

    Mar 21, 2024

  • 2024 Innovative Practices Winners in Informatics, Collaboration, Clinical IT, Genomics

    Bio-IT World | Bio-IT World today announced the 2024 Innovative Practices Awards winners. Six projects were honored. Companies driving the winning entries included AstraZeneca, DNAnexus, Pistoia Alliance, Regeneron, Tempus, and UK Biobank.

    Mar 19, 2024

  • Five Global Teams Tackling Cancer Grand Challenges

    Bio-IT World | Cancer Grand Challenges—a global funding initiative co-founded by the National Cancer Institute and Cancer Research UK—has announced five new global teams selected to each receive up to $25M over five years to take on four of cancer’s toughest challenges.

    Mar 14, 2024

  • Citizen-Driven Research Aids Development Of Digital Biomarkers For ALS

    Bio-IT World | When it comes to research on amyotrophic lateral sclerosis (ALS), every stakeholder—most especially patients—knows time is of the essence. From diagnosis to death, life expectancy from the debilitating neuromuscular disease can be two years or less.

    Mar 13, 2024