• How Large Language Model-Based AI Will Transform Drug Safety & Regulatory Processes

    Bio-IT World | Training and validating intelligent automation systems for life sciences R&D purposes can undermine the business case. But the large language models (LLMs) used to power Generative AI (GenAI) is changing that and bolstering compliance, enabling on-the-fly data discovery, “in context” learning, and narrative extrapolation.

    Jul 12, 2024

  • New Biomarker Offers Hope of Detecting Alzheimer's in Asymptomatic Stages

    Bio-IT World | Until recently, all the available therapeutic options for treating Alzheimer’s disease were designed to reduce symptoms rather than address causes of the disease. But with two beta-amyloid antibodies now approved by the U.S. Food and Drug Administration, and tau-targeting agents in clinical trials, hopes are rising that Alzheimer’s progression can be delayed if not stopped.

    Jul 10, 2024

  • Illumina Acquires Fluent BioSciences Single-Cell Technology

    Bio-IT World | Illumina has acquired Fluent BioSciences, developer of an emerging and highly differentiated single-cell technology. Fluent Biosciences is now a wholly owned subsidiary of Illumina and was acquired with cash on hand.

    Jul 9, 2024

  • Regeneron Uses Voice-to-Text for Science-First Data Digitization Efforts for Animal Research

    Bio-IT World | When Regeneron began exploring how to digitize scientific information in lab environments, IT engineers didn’t begin by brainstorming their own ideas. They began by shadowing scientists.

    Jul 9, 2024

  • Building On Biotech Confidence With Strategic R&D

    Bio-IT World | The biotech sector has weathered some recent headwinds in the funding market but is marked by a general air of confidence as we come to close the first quarter of 2024. This confidence was noted in our recent survey of over 130 decision makers in biotech companies, where we found that despite challenging conditions, 87% of respondents reported at least some confidence and 38% were very confident in the overall success of their product.

    Jul 1, 2024

  • Follow the Money: Foresite Capital Invests in Groundbreaking Tech, Synthesizing Therapeutic Cytokines, More

    Bio-IT World | Foresite Capital launches new fund for groundbreaking technologies, ranging from novel therapeutics to companies at the intersection of technology and biotechnology; Bright Peak Therapeutics intends to advance platform that allows for the conjugation of its enhanced cytokines as payloads to certain antibodies, creating novel and proprietary “Bright Peak Immunocytokines”; more.

    Jun 27, 2024

  • Illumina Appoints New CCO, Launches New Software Version, PacBio Launches Free HiFi Long-Read Variant Frequency Database, More

    Bio-IT World | Illumina has appointed Everett Cunningham as Chief Commercial Officer (CCO) and has also announced the launch of DRAGEN v4.3, the latest version of its DRAGEN software; PacBio, in collaboration with the international Consortium for Long-Read Sequencing (CoLoRS), announced the launch of the first publicly available and free HiFi long-read variant frequency database with global representation; more.

    Jun 26, 2024

  • Unified Under a Universal Language: The Pistoia Alliance’s IDMP Ontology

    Bio-IT World | Identification of Medicinal Products (IDMP) implementation greatly varies across organizations and regulatory jurisdictions, which impacts drug safety and pharmacovigilance. To ensure that organizations around the world can use a universal semantic interoperability based on FAIR data principles, the Pistoia Alliance has built an IDMP Ontology (IDMP-O Release 1), augmenting existing ISO IDMP standards set by the European Medical Agency.

    Jun 25, 2024

  • When Banks Say ‘No’ to Equipment Financing, It’s Not the End of the Story

    Bio-IT World | Thanks to emerging technologies, from generative AI to data platforms and robotic solutions, companies in the biotech and life science sectors are achieving amazing advances. But for every headline showcasing a success, there is a reminder of the abiding industry reality: countless promising companies are still struggling to acquire the equipment and technology they need to fuel product development and platform growth.

    Jun 21, 2024

  • Avoiding the Traps and Pitfalls of Artificial Intelligence Development

    Bio-IT World | Artificial intelligence (AI) was the main topic at the 2024 Bio-IT World Conference & Expo. While there was much excitement over new developments, there were also many discussions covering the obstacles that block the path to further progress—many of which have nothing to do with technology or data.

    Jun 19, 2024

  • Regeneron’s Platform Play for Protein Prediction at Scale

    Bio-IT World | AlphaFold was revolutionary to protein scientists and their work, but as soon as the new capabilities became clear, scientific demand exploded. Regeneron engineers used the AlphaFold2 model to create a custom, cloud-based solution to allow analysis of thousands of protein binding partners in parallel.

    Jun 18, 2024

  • Ruth Marinshaw on the State of Data in the Academic Sphere

    Bio-IT World | Data is a double-edged sword in the industry. It is a necessary tool for technological developments, especially artificial intelligence (AI), but the excess generation of data has become a thorn on the sides of researchers and companies. And for universities, they have their own sets of problems to deal with.

    Jun 13, 2024

  • UK Biobank Pivoting to Platform-Only Model For Big Data Sharing

    Bio-IT World | When it comes to big data, the largest amount comes from whole genome sequencing (WGS). At the population scale, WGS produces petabytes of information that for sharing purposes requires cloud computing capabilities. That realization came early to UK Biobank.

    Jun 12, 2024

  • NVIDIA Launches Generative AI-in-a-Box

    Bio-IT World | At COMPUTEX Taipei earlier this month, NVIDIA launched NIM—NVIDIA Inference Microservices—a simple, standardized way to add generative AI to applications. Data generation—rather than retrieval—is poised to take over computing.

    Jun 11, 2024

  • Automating FAIR, Clean Data Generation from Flow Cytometry at Regeneron

    Bio-IT World | Ronald Realubit, Principal Scientific Business Analyst (Therapeutic Ab Development) at Regeneron, presented a map of the Regeneron team members behind the Automated High-Throughput Flow Cytometry Data Processing Pipeline project, highlighting 38 team members by name. The pipeline was one of three Regeneron projects that won a 2024 Bio-IT World Innovative Practices Award, all sharing the “Informatics to Achieve Operational Excellence” category.

    Jun 6, 2024

  • Precise, Integrated Gene Correction and Integration Offers Therapeutic Benefits

    Bio-IT World | During his keynote address at last month’s PEGS Boston, David Liu, director of the Merkin Institute of Transformative Technologies in Healthcare, vice-chair of the faculty at the Broad Institute of MIT and Harvard, and a Howard Hughes Medical Institute investigator, described how the laboratory evolution of gene editing systems has enabled efficient and programmable gene correction or even whole gene integration.

    Jun 5, 2024

  • Oxford Nanopore’s Clive Brown Looks Back and Ahead

    Bio-IT World | The Oxford Nanopore vision was of a “new generation of single-strand sequencing technology, featuring accurate long reads of single-stranded DNA molecules,” Bio-IT World reported from the 2012 event. Today, Brown’s big ideas include whole-chromosome sequencing, flow cell loading without a pipette, and advances in chemistry, electrical engineering, and commercial format.

    Jun 4, 2024

  • Pan-RAS Inhibitor Offers Hope of Improved Pancreatic Cancer Prognosis

    Bio-IT World | A consortium of pancreatic cancer researchers sharing information in real time has shown that an oral pan-RAS inhibitor known as RMC-7977, developed by Revolution Medicines, effectively targets the common cancer-causing RAS proteins while minimally impacting normal cells—and did so across a comprehensive range of preclinical models in a series of similar experiments.

    May 30, 2024

  • Ambry Genetics, PacBio Take on Rare Diseases, Regeneron Makes TOP500 List, More

    Bio-IT World | Ambry Genetics and PacBio to support the Pediatric Mendelian Genomics Research Center (MGRC) program to better understand the underlying biology of rare diseases; Recursion’s BioHive-2 was dubbed No. 35 on the latest TOP500 list of the world’s fastest supercomputers; the Catalogue of Somatic Mutations in Cancer (COSMIC) launches its 100th version; more.

    May 29, 2024

  • Follow the Money: Funds for Alzheimer’s Research, CN Bio Accelerates Oncology Products, More

    Bio-IT World | Laurence Belfer gifts funds to MD Anderson Cancer Center to strengthen neurodegeneration research through the Belfer Neurodegeneration Consortium; CN Bio plans to accelerate its expanding product portfolio; more.

    May 28, 2024