• Glowing Cholesterol A Game-Changer For Study Of Heart Disease

    Bio-IT World | A new technique that lights up a protein shuttling LDL cholesterol around the circulatory system has made it financially feasible to do high-throughput screening for cardiovascular drugs as well as measure the size of LDL particles—an important but poorly-understood disease risk factor.

    Sep 13, 2019

  • Why Aren’t There Better Cancer Drugs? Scientists May Have Picked the Wrong Targets

    The New York Times | Drugs can stop cancer cells if they attack the right proteins. But many of these targets were chosen with dated, imprecise technology, a new study suggests.

    Sep 12, 2019

  • Optimizing Storage to Address Workflow Challenges in Biotech and Life Sciences Applications

    Bio-IT World  Digital transformation is no longer just a buzzword: it is an inescapable truth for many industries, including life sciences, and data storage is at the heart of this digital revolution.

    Sep 9, 2019

  • Big Data Biobanks Aren't Equally Open To Researchers

    NPR.org | Medical and genetic data from more than a million Americans are now in scientific databases. Some programs hoard the data, while others share widely with scientists, hoping to speed medical discovery.

    Sep 6, 2019

  • Evidence-Based Variant Interpretation For The Modern Era

    Bio-IT World | Next Generation Sequencing has ushered in a new era of high-throughput genomic analysis and increased our ability to understand the molecular basis behind disease. While the capacity for generating genetic data has exploded, the capacity to interpret the meaning of this data has lagged. It was these issues that led the team at Genomenon to create Mastermind and, more recently, Mastermind Reporter.

    Sep 4, 2019

  • Q-State, LUCA Biologics, AskBio, And More: News From August 2019

    Bio-IT World | August featured exciting new, products, and partnerships from around the bio-IT community from innovating companies, organizations, and universities, including Q-State, LUCA Biologics, AskBio, and more.

    Aug 29, 2019

  • NIH Announces Genomic Innovator Awards Winners

    Bio-IT World | The National Human Genome Research Institute announced the winners of their Genomic Innovator Awards. Researchers from the University of Nebraska Medical Center, Omaha; Vanderbilt University Medical Center; Harvard Medical School, Boston; Massachusetts General Hospital, Boston; The City of Hope Comprehensive Cancer Center, Duarte, California; and the University of Maryland-Baltimore were honored.

    Aug 28, 2019

  • Microway Provides Vyasa Analytics With NVIDIA DGX-1, NumberSmasher GPU Server

    Bio-IT World Brief | Microway announced it has provided an NVIDIA DGX-1 supercomputer and Microway NumberSmasher Tesla GPU Server to Vyasa Analytics.

    Aug 26, 2019

  • Researchers Beginning To Use CRISPR In Studies

    Bio-IT World | After years of discussion, patent lawsuits, and hype, the gene-editing tool know as CRISPR is finally making its way into clinical trials.

    Aug 26, 2019

  • The Next Trick For CRISPR Is Gene-Editing Pain Away

    MIT Technology Review | A family of street performers could walk on coals. Scientists have paired the discovery with the gene-editing tool CRISPR, in what they say is a step toward a gene therapy that could block severe pain caused by diabetes, cancer, or car accidents without the addictive effects of opioids.

    Aug 23, 2019

  • Color Receives Genetic Counseling Grant for All of Us

    Bio-IT World  | The All of Us research program has awarded $4.6 million in initial funding to Color, a health technology company in Burlingame, California, to establish the program’s nationwide genetic counseling resource. Through this funding, Color’s network of genetic counselors will help participants understand what the genomic testing results mean for their health and their families.

    Aug 21, 2019

  • U.K. Firm Creates Operating System To Handle Massive Genomic Patient Data Sets

    Forbes | We're making work digital on every desktop, we're empowering digital sensors in the Internet of Things (IoT) on every street corner, we're building smart digital AI-powered IT systems with machine learning and decision-making abilities to automate our lives… and we're digitizing ourselves as well.

    Aug 16, 2019

  • 20% Enrollment For All of Us Program, Challenges Remain

    Bio-IT World | The All of Us research program announced updates today in a special report published in the New England Journal of Medicine. As of July 2019, the All of Us program has enrolled more than 175,000 core participants (those who contributed personal information, biospecimens, and physical measurements and who agreed to share EHR data) and more than 230,000 total participants; an additional 40,000 participants have registered on the website, the authors report. “More than 80% of these participants are from groups that have been historically underrepresented in biomedical research,” the authors observe.

    Aug 15, 2019

  • Tackling the Affinity Gap at Amgen

    Bio-IT World At Amgen, Agnieszka Kielczewska had a problem. The AMGN12 antibody, derived from an in vivo immunization of the XenoMouse, demonstrated single digit pM affinity to the human orthologue of the target protein, but a 200-fold weaker binding to the monkey orthologue. In order to conduct toxicology studies in non-human primate species, Amgen needed that affinity difference to be closer to 10-fold.

    Aug 14, 2019

  • Nvidia just made it easier to build smarter chatbots and slicker fake news

    MIT Technology Review | Chipmaker Nvidia is betting that AI's language skills will advance rapidly-it's releasing a powerful tool for putting together chatty programs.

    Aug 13, 2019

  • Biobanking Is Changing The World

    Forbes | With the evolution of biobanks rapidly enabling the creation of massive collections of biological material and associated information, how are these collected terabytes of data transforming nations?

    Aug 13, 2019

  • National Genomic Data Initiatives: A Worldwide Update

    Bio-IT World | The global movement toward the application of genomics to medical practice is exciting because it is essentially "precision medicine come real," says Ewan Birney, chair of the Global Alliance for Genomics and Health (GA4GH). But which countries are involved? And what progress has been made so far? Bio-IT World’s overview offers an update on currently active national government-funded genomic-medicine initiatives, grouped by area of emphasis.

    Aug 12, 2019

  • Bacteria On Tumors Influences Immune Response, Survival Of Patients With Pancreatic Cancer

    Bio-IT World News Brief | A team led by researchers from The University of Texas MD Anderson Cancer Center reports that a key difference between the few pancreatic cancer patients who survive long-term and the many whose disease overcomes all treatments is the bacterial signatures on their tumors that either stimulate or suppress immune response.

    Aug 9, 2019

  • Patentable Subject Matter In Bioinformatics After USPTO’s January Guidance: Easier To Obtain, But Harder To Keep

    Bio-IT World Contributed Commentary | The United States Patent and Trademark Office released new guidance earlier this year that appears to have somewhat reversed the trend of increased patentable subject matter ineligibility for bioinformatics patent applications.

    Aug 5, 2019

  • CRISPR Patents, Oxford Nanopore, Komodo Dragons, And More: News From July 2019

    Bio-IT World | July featured exciting news, products, and partnerships from around the bio-IT community including CRISPR patents, Oxford Nanopore, the first high-resolution sequence of the Komodo dragon, and more.

    Jul 31, 2019