• Could Death Receptor 5 Antibodies Make A Comeback?

    Bio-IT World | Big pharma has invested billions of dollars in developing antibodies targeting death receptor 5 (DR5) over the years in hopes of improving the survival of patients with cancer. While promising when tested in mice in the lab, they invariably failed to show efficacy during phase 2 clinical studies. But researchers at the University of Virginia now have a new theory that could revive them.

    May 4, 2021

  • Sequencing Project for Developmental Differences, New Data Management Tools, Hyperscale Storage, More

    Bio-IT World | NIH grant tackles COVID-19 disparities, St. Jude launches historic expansion, Illumina all in on African Pathogen Genomics Initiative, and new platforms and services to ease drug and vaccine development. Plus: new storage from VAST Data, and new solutions for tracking research papers and patents.

    May 3, 2021

  • Big Money for Gene Editing, Engineering, Structure-Based Drug Design, and Data Management

    Bio-IT World | Illumina joins the Gates Foundation in a global pathogen genomics initiative, new money for immune profiling, and Benchling nets $200M for their cloud platform.

    Apr 29, 2021

  • Understanding Proteins With Natural Language Processing

    Bio-IT World | New research from the departments of chemistry and physics at Cambridge University has just helped demonstrate the potential of natural language processing (NLP) for understanding biomolecular condensates.

    Apr 28, 2021

  • New Event Launching in June Focusing on AI for Pharmaceuticals

    Bio-IT World | Bio-IT World and AI Trends are pleased to announce DECODE: AI for Pharmaceuticals, June 7-9, 2021, the first cross-functional conference to uncover AI’s true value for the pharmaceutical sector, while also focusing on data strategies, organizational change management, and implementation best practices.

    Apr 26, 2021

  • Why Prioritizing Genomic Research Is Critical for The Future of Healthcare

    Bio-IT World | Over the past 20 years, the field of genomics has undergone significant progress and transformation. We are at an exciting juncture in this field; however, there is more to be done to ensure more equitable access to technologies and support researchers around the world.

    Apr 23, 2021

  • Bioinformatics Platform Designs Therapies Against Multi-Drug Resistant Bacteria

    Bio-IT World | A Johns Hopkins University team has published details of their Facile Accelerated Specific Therapeutic (FAST) platform in Nature Communications Biology, a platform designed to address antibiotic resistance.

    Apr 22, 2021

  • How COVID-19 Is Changing the Sequencing Landscape

    Bio-IT World | The pandemic has prompted diverse scientific groups to take on sequencing in the US—and for many, the new technology has brought additional challenges to overcome. But these NGS-newbies are learning and will change biology beyond COVID-19.

    Apr 20, 2021

  • COVID-19 Highlights the Need for Interoperability in Healthcare

    Bio-IT World | In healthcare, the primary means of collecting patient data, the electronic health record (EHR), is one of the biggest offenders of a siloed approach to data. One need look no farther than the current pandemic to see how the lack of data-sharing infrastructure has prevented healthcare providers from getting a complete picture of their patients’ medical histories and hindered research on what treatments are working against the novel coronavirus.

    Apr 16, 2021

  • Bayer’s Science@Scale Platform and the Role For NVIDIA Federated Learning

    Bio-IT World | NVIDIA has announced the next generation of federated learning: Clara 4.0 with global orchestration of edge clients, and an addition to privacy-preserving homomorphic encryption. David Ruau, VP, head of Global Data Assets and Decision Science at Bayer, outlined Bayer’s work with NVIDIA to incorporate Clara Federated Learning.

    Apr 15, 2021

  • Mutational Signatures In Cancer Improved By Supervised Machine Learning

    Bio-IT World | Researchers at the Johns Hopkins Kimmel Cancer Center have a newly developed supervised machine learning algorithm that does the best job yet of connecting tissue-specific cancers to potential disease-driving factors.

    Apr 14, 2021

  • Pharma, Life Sciences Partnerships Driven By NVIDIA AI and Processors

    Bio-IT World | At NVIDIA’s GTC event starting this week, NVIDIA CEO Jensen Huang outlined—among other things—partnerships expanding Clara Discovery, NVIDIA’s computational platform for healthcare.

    Apr 12, 2021

  • Collaboration Is Key to Combatting Cybercrime

    Bio-IT World | Cybersecurity challenges have only escalated during the COVID-19 crisis, particularly in the fields of science and healthcare. The past year has seen a dramatic increase in the number of breaches and ransomware attacks for the enterprise networks of labs and healthcare facilities.

    Apr 9, 2021

  • Drugs Repurposed To Tap Immune System In Fight Against Pathogens

    Bio-IT World | Researchers at the University of California (UC), San Diego have proposed that the definition of antibiotic resistance be broadened to include treatment failure among patients on appropriate antibiotic therapy, which still encompasses the “great majority of unsuccessful outcomes in infectious disease.

    Apr 6, 2021

  • Follow the Money: Single-Cell Multiomics, Data Networks, Security

    Bio-IT World | New investment funds for late-stage companies and public health. Next-gen genomic medicines and single-cell multiomics get cash, and PatientsLikeMe raises a new round of funding to expand.

    Apr 1, 2021

  • Viruses (And People) Play A ‘Signaling Game’ With Strangers And Dangers

    Bio-IT World | Mathematically speaking, the cytokine storm seen with severe COVID-19 and the out-of-control behavior of QAnon conspiracy theorists are not really all that different, according to Bud Mishra, a professor at New York University's Courant Institute of Mathematical Sciences. Both invoke a stranger-danger “signaling game” that would also explain how messenger RNA (mRNA) and transfer RNA (tRNA) came to be cellular co-occupants some three and half billion years ago.

    Mar 31, 2021

  • Global Research Spanning 30+ Countries to Examine COVID’s Impact on the Brain

    Bio-IT World | While it isn’t clear just yet how the coronavirus could impact cognition over the long haul, a global group of researchers is looking to learn more.

    Mar 30, 2021

  • 5 Important AI Discoveries Generated by COVID-19

    Bio-IT World | Life sciences leaders are outlining the learnings from COVID-19 to move forward, hopefully stronger, wiser, and better than before.

    Mar 26, 2021

  • New Framework For Developing Polygenic Risk Scores

    Bio-IT World | Last week a research team published a 22-item framework in Nature that identifies the minimal polygenic risk score-related information that scientists should include in their studies.

    Mar 25, 2021

  • Eric Dishman on Paul Allen, Andy Grove, and All of Us

    Bio-IT World | TRENDS FROM THE TRENCHES—It’s been a little over a year since Eric Dishman stepped down as CEO of the National Institutes of Health’s All of Us program and took on the role of Chief Innovation Officer. Now he talks about his early training under Paul Allen of Microsoft and Andy Grove of Intel still plays into his decisions.

    Mar 23, 2021