• Export Of Damaged Mitochondria To The Heart May Explain ‘Obesity Paradox’

    Bio-IT World | Exosomal trafficking from fat to heart cells may help explain the “obesity paradox,” the baffling observation that packing extra pounds can have a beneficial, if short-term, protective effect for patients with heart disease. The cargo being delivered are oxidatively damaged mitochondrial particles that appear to prompt the heart to produce a flood of protective antioxidant molecules, better preparing it to cope with insults that later come along—such as a heart attack.

    Oct 12, 2021

  • Follow the Money: CRISPR, Next-Gen Neuroscience, Protein Platforms

    Bio-IT World | CRISPR unicorn, pan-coronavirus vaccine research, chemical and biological weapons protection for warfighters, new methods for live cell research, seed round for a new drug discovery platform, and more.

    Oct 11, 2021

  • Amazon Genomics CLI is Open Source, UK Biobank’s Research Analysis Platform Live, More

    Bio-IT World | New leadership at JAX, Illumina expands into Latin America, PacBio partners with The European Reference Genome Atlas, UK Biobank’s Research Analysis Platform is now live, and BC Platforms seeks to build the largest integrated clinical and genomics data biobank in Africa. Plus: new products from MemVerge, Quantum, Pure Storage, Sensyne Health, and more.

    Oct 7, 2021

  • Pistoia Alliance Gauges Life Sciences’ Quantum Computing Outlook

    Bio-IT World | The Pistoia Alliance surveyed life sciences professionals this summer to gauge their understanding of quantum computing. They found that almost half classify their understanding of quantum computing (QC) technology at beginner level only. These results, the Alliance argues, show that despite significant noise around the potential of QC, few life science organizations or individuals are yet able to apply the technology.

    Oct 6, 2021

  • Trends from the Trenches 2021: Where Bio-IT Stands on Digital Transformation, Data Transformation, AI/ML

    Bio-IT World | Chris Dagdigian wasn’t the only speaker at the Bio-IT World Conference & Expo Trends from the Trenches session. He also welcomed Adam Kraut, Karl Gutwin, and Fernanda Foertter—all BioTeam or former BioTeam consultants—to report on trends in digital transformation, data transformation, and AI/ML.

    Oct 5, 2021

  • Speeding Toward Innovation: How Intelligent Search Accelerates Drug Development

    Bio-IT World | Cognitive search—and the intelligence and analytics that go with it—could well be the key element for optimizing innovation and improving the efficiency of research, clinical trials, and regulatory processes.

    Oct 4, 2021

  • NIH Distributes $185M for Impact of Genomic Variation on Function (IGVF) Consortium

    Bio-IT World | At the beginning of September, the National Institutes of Health launched the Impact of Genomic Variation on Function (IGVF) consortium, a new initiative of NIH’s National Human Genome Research Institute (NHGRI). Now, NHGRI has named the first 25 awards across 30 U.S. research sites totaling approximately $185 million over five years.

    Sep 29, 2021

  • Trends in the Trenches 2021: Chris Dagdigian on Security Vaporware, Egnyte, and the Data Management Culture

    Bio-IT World | At this year’s Trends from the Trenches plenary presentation, Chris Dagdigian brought an overview of the trends and a warning of the technology pitfalls facing the Bio-IT community. He continued to beat his drum on a few cultural issues Bio-IT still needs to address, and he alerted the community to what’s new and notable.

    Sep 28, 2021

  • A Pandemic-Driven Digital Transformation: What Will Stick for Life Sciences

    Bio-IT World | Namita Limaye, Research VP at IDC, gave a broad overview of IDC’s survey findings over the past 18 months at this week’s Bio-IT World Conference and Expo held in Boston and online. She highlighted trends in the life sciences that included increased collaboration, speedier adoption of technologies, and a look at how executives are viewing—and planning—digital transformation.

    Sep 23, 2021

  • All of Us Update: Nearing Half a Million Participants, Whole Genomes Available This Winter

    Bio-IT World | Josh Denny, CEO of the All of Us research program, gave an update during the Bio-IT World Conference & Expo this week held in Boston and online.

    Sep 22, 2021

  • Digital Transformation: Execs Weigh in on the New Future for Pharma

    Bio-IT World | The Bio-IT World Conference and Expo kicked off last night both in Boston and online. The hybrid event welcomed attendees in person for the first time since April 2019, starting with an expansive plenary panel on digital transformation—a process that has been kicked into high gear for many companies during the pandemic.

    Sep 21, 2021

  • Enabling Scalability of Cell & Gene Medicines with Connected Lab Cold Storage

    Bio-IT World | Many cell and gene researchers are turning to technology to assist in scaling their operations. Connected and intelligent equipment is also becoming crucial for developers to meet research goals and maintain compliance, including connected ultra-low temperature (ULT) and cryogenic freezers capable of communicating temperature changes, product safety, and more.

    Sep 17, 2021

  • Building an Agile Approach to Antibody Discovery

    Bio-IT World | When the senior leaders at Eli Lilly and Company heard Helen Li’s plan for the pharma’s new Biologica platform for harvesting company institutional knowledge and building an analytic engine to suggest high quality antibody molecules for early discovery pipeline, they had one challenge: do it faster. And so, Li’s team launched an accelerated, agile development plan to build a platform they envisioned to house all experimental data, that feed into in silico modeling, a platform to scale up analytics to empower quality by design.

    Sep 16, 2021

  • Liverpool, Others Launch Forward-Looking Pandemic Research Initiatives

    Bio-IT World | Yesterday the University of Liverpool and other partners launched the Pandemic Institute, a medical, academic and civic partnership aiming to accelerate the global response to pandemics, unify global intelligence, and increase the reach and impact of pandemic research.

    Sep 14, 2021

  • GSK’s Digital Transformation Roadmap

    Bio-IT World | When Mike Montello joined the GSK team, the first steps of the pharma’s digital transformation had already taken place. Now with GSK’s spin-off of its consumer business looming, Montello is tasked with accelerating adoption of digital, data, and analytics to improve the overall research and development productivity—and increase probability of success of new medicines and vaccines.

    Sep 13, 2021

  • The Practical, Near-Term Future for Synthetic Biology

    Bio-IT World | Trends from the Trenches | Aoife Brennan left the practice of medicine to explore biotech. Now she leads Synlogic, developing scientific strategy for the company’s practical applications of synthetic biology. Brennan spoke about her career journey and the future of synthetic biology—a preview of her upcoming talk at the Bio-IT World Conference & Expo.

    Sep 9, 2021

  • A Closer Look at Type 1 Diabetes Causal Variants

    Bio-IT World | Researchers from the University of Virginia and the University of Oxford have been tracing the genes responsible for type 1 diabetes for years. The team just published the largest look yet: exploring the genomes of more than 61,000 individuals of diverse ancestry to better understand the genetic underpinnings of this complex disease.

    Sep 7, 2021

  • Follow the Money: Next Gen Oligonucleotides, ML Insights Platform

    Bio-IT World | HealthTech SPAC funding, wearable fitness program for metabolic health disorders, multiple academic grants for dementia research, using AI to watch cells over time, and more.

    Sep 3, 2021

  • New Results from BabySeq, Pharmacogenomic Updates, New Products

    Bio-IT World | Harvard-Israel and Sema4-Avera launch precision medicine partnerships, Rice announces new Genetic Design and Engineering Center, Foundation Medicine partners with Epic, and Amgen and USC provide cryo-TEMs. Plus new products from BioIVT, BD.

    Sep 1, 2021

  • Artificial Intelligence Calculates Anti-Aging Properties Of Compounds

    Bio-IT World | Artificial intelligence (AI) has been paired with one of the simplest of organisms—the nematode Caenorhabditis elegans—to enlighten the scientific community about the physical and chemical properties of drug compounds with anti-aging effects.

    Aug 31, 2021