• Pan-European Genomic Reanalysis Effort Yields Over 500 Diagnoses

    Bio-IT World| A groundbreaking collaborative effort spanning 12 European countries and Canada has successfully identified genetic causes for more than 500 previously unsolved rare disease cases. Led by the University of Tübingen in Germany, the Solve-RD (Solving the Unsolved Rare Diseases) consortium brought together 300 experts from 37 institutions to leverage advanced genomic reanalysis techniques, ultimately providing long-awaited answers to patients and their families.

    Mar 6, 2025

  • High-Performance Computing in the AI Era: Challenges and Future Prospects

    Bio-IT World| In an era where artificial intelligence (AI) dominates discussions in technology, high-performance computing (HPC) remains the backbone of scientific discovery and enterprise research. Despite its critical role, HPC often operates in the background, much like electricity—only noticed when it fails. On the latest Trends from the Trenches Podcast, Dirk Petersen, Director of the Supercomputing Center at Oregon State University, shared his insights on the evolving role of HPC and its integration into AI-driven research.

    Mar 5, 2025

  • AI to Democratize Access to Cheap, High-Throughput Cardiotoxicity Testing

    Bio-IT World| Researchers have trained an artificial intelligence (AI) model to reconstruct the electrical signals inside of heart cells based on recordings taken from outside those cells, opening the possibility of cheap, high-yielding cardiotoxicity testing using commercially available microelectrode arrays. The hope is that the U.S. Food and Drug Administration (FDA) will allow the tool to be used in lieu of inserting pipettes into cells to record signaling changes with the addition of a drug, which is both costly and cumbersome to do at scale.

    Mar 4, 2025

  • The False Dichotomy of Short Reads vs. Long Reads

    Bio-IT World| The rate of evolution of DNA sequencing technologies since the introduction of the Sanger method in the 1970s has been astounding. It’s just over 20 years since the publication of the first draft human genome and today, technologies can deliver that same information for as little as $100.

    Feb 28, 2025

  • RNA in Oncology Research, Ultima Genomics Commercially Launches Platform, More

    Bio-IT World| InfoBionic.Ai’s MoMe ARC delivers real-time cardiac insights, empowering physicians to improve patient outcomes; Ultima Genomics announced the commercial launch of UG 100 Solaris; and more.

    Feb 27, 2025

  • Follow the Money: 3D Spatial Biology, AI-Powered Imaging Biomarkers, More

    Bio-IT World| Stellaromics commercializes their 3D spatial biology platform, Pyxa; Latent Labs’ AI platform shows promising potential to open new paths to personalized medicines; and more.

    Feb 26, 2025

  • Eli Lilly’s CISO Andrea Abell on Safeguarding Innovation in Pharma

    Bio-IT World| Earlier this week at the ViVE conference in Nashville, Tenn., Bio-IT World editor, Allison Proffitt, sat down with Andrea Abell, Eli Lilly’s Chief Information Security Officer (CISO), whose mission is to protect the integrity of pharmaceutical research from inception to patient delivery. Together they discussed the critical role cybersecurity plays in Lilly’s broader goal of bringing life-changing medicines to market.

    Feb 20, 2025

  • Illumina’s New Spatial Products

    Bio-IT World| Today, Illumina announced a new spatial technology program of Illumina sequencers and a multimodal analysis platform. The company also announced a collaboration with the Broad Institute on spatial transcriptomics. Illumina's spatial technology delivers unbiased whole-transcriptome profiling with cellular resolution and high sensitivity.

    Feb 19, 2025

  • AI in Healthcare: How To Assess What Works

    Bio-IT World| At a panel discussion this week at the ViVE conference in Nashville, Tenn., researchers and physicians discussed the promise and hype of AI. Moderated by Alexander Morgan, partner at Khosla Ventures, the discussion was wide ranging and discussed the AI tools ready for use by physicians; which classes of AI are not yet delivering; and how to assess what’s right for you.

    Feb 18, 2025

  • Ultima Genomics Sequencing Platform Selected for UK Biobank Study

    Bio-IT World| Last month, Ultima Genomics announced that their UG 100 sequencing platform was selected by UK Biobank to be used in their human proteomics study, which is anticipated to be the largest and most comprehensive proteomics study to date. The study is intended to quantify more than 5,400 protein markers across 600,000 samples, which will help researchers understand how protein levels fluctuate over time and how these changes correlate with disease progression and aging.

    Feb 14, 2025

  • Epigenetics Alone Can Alter Cancer Susceptibility

    Bio-IT World| Evidence is emerging that epigenetic differences prior to birth can signal the type of cancer that occurs decades later by dictating which mutated cells turn into a tumor. It is “underappreciated” that most otherwise healthy people are walking around with cancer-causing mutations that their body suppresses unless their built-in defense system mysteriously fails.

    Feb 13, 2025

  • Lifebit, Psifas Partner for Israeli Genomic Medicine Initiative

    Bio-IT World | On the heels of its announced collaboration with 23andMe, Lifebit, has announced a long-term partnership with Psifas, Israeli Genomic Medicine Initiative. This collaboration will empower groundbreaking advancements in personalized medicine by providing a secure and unified platform for clinical-genomic research across Israel’s diverse population.

    Feb 10, 2025

  • Crystal Ball: At JP Morgan, Companies Predict Trump Administration Impacts

    Bio-IT World| Market questions always arise with the changing of presidential administration in the United States, though this year’s uncertainty seems a bit heightened. Expected outlooks to NIH funding and other regulatory and even Department of Government Efficiencies (DOGE) changes came up in analyst questions after some of the presentations at the J.P. Morgan Healthcare Conference last month.

    Feb 6, 2025

  • 10X Genomics at JPM: New Products, New Sales Team, New Markets

    Bio-IT World | 10X Genomics launched a spate of new products in 2024 in both their single cell and spatial areas. “Our view is that eventually, every relevant sample will need to be analyzed with single cell and spatial context,” said Serge Saxonov, 10X CEO and co-founder, in his 2025 J.P. Morgan Healthcare Conference presentation.

    Feb 5, 2025

  • Recursion at JPM: Exscientia Merger and the Coming Virtual Cell

    Bio-IT World | Chris Gibson, CEO of Recursion, gave the company update last month at the 2025 J.P. Morgan Healthcare Conference. Gibson gave updates on several Recursion pipeline programs for indications including precision oncology, rare disease, and other indications. He also gave updates on the merger with Exscientia and the coming virtual cell.

    Feb 4, 2025

  • Redefining Storage to Enable Digital Twins

    Bio-IT World | While the concept of digital twins is similar in life sciences to manufacturing, human bodies are significantly more complex than industrial machines and systems, amplifying the challenges surrounding data generation, management, and analysis. Making effective use of the data required to advance digital twin research creates immense infrastructure challenges.

    Jan 30, 2025

  • Follow the Money: Obesity, COPD, Universal AI for Biology

    Bio-IT World | January saw new company launches in COPD and small molecules, as well as investments targeting genetic engineering, epigenome editing, regenerative medicine, and more.

    Jan 29, 2025

  • GSK’s $1B Acquisition, Roche Licenses Gene Therapy, New Products, More

    Bio-IT World | 23andMe launches a new research offering after mass resignation by their board, new multi-omics tool from Enhanc3D Genomics, Absci and Owkin announce an AI partnership, a new cloud-based vivarium platform from Charles River, and more.

    Jan 28, 2025

  • Radio Frequencies Show Potential in Treating Alzheimer’s Disease

    Bio-IT World | Through a fortunate stroke of serendipity 15 years ago, researchers experimenting with a mouse model of Alzheimer’s disease found that radio frequency (RF) energy could improve cognitive health. It was not unlike the discovery of penicillin based on the unexpected appearance of a bacteria-killing mold in a petri dish.

    Jan 23, 2025

  • Mount Sinai Develops AI Prediction Tool for Cancer Patient Response to ICI Therapy

    Bio-IT World | Researchers at the Tisch Cancer Institute at Mount Sinai, in collaboration with Memorial Sloan Kettering Cancer Center (MSKCC), have developed SCORPIO, an artificial intelligence (AI) tool that can predict how well patients with cancer will respond to immune checkpoint inhibitor (ICI) therapy by analyzing routine blood tests and clinical data.

    Jan 22, 2025