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Harvard's Boguski Rides Genomics' Third Wave
GEN | A new health services business, Genome Health Solutions, co-founded by pathologist Mark Boguski and Richard Kellner, is looking to catch the emerging third wave in the clinical application of genomics by marrying knowledge of the clinical and technology market space.
Jul 3, 2012
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The Return of Finished Genomes: Hybrid Sequencing Strategy Boosts Pacific Biosciences Accuracy, Assembly
Bio-IT World | Two new papers in Nature Biotechnology – one from Cold Spring Harbor Laboratory, the other from Pacific Biosciences – demonstrate the value of combining long but relatively error-prone reads from a “3rd-generation” single-molecule instrument with the high-throughput, shorter “2nd-generation” read lengths from Illumina, marking a potential breakthrough in the quest for "finished genomes."
Jul 2, 2012
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Bristol’s $5.3 Billion Amylin Deal Heralds Acquisition Hunger
Bloomberg | Bristol-Myers Squibb's $5.3 billion deal to buy diabetes drugmaker Amylin Pharmaceuticals is the largest for the pharmacuetical industry industry this year, and comes after the firm's top-selling drug, the blood- thinner Plavix, faced generic competition for the first time in May.
Jul 2, 2012
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Sophic Releases Cancer Biomarker Database
Bio-IT World | Funded by a 3-year-SBIR grant from the NCI, Sophic has released a cancer biomarker database called SCan-Mark Explorer, focused on breast, ovarian, colon, non-Hodgkin’s lymphoma, and melanoma.
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Wellcome Trust Gets Tough With Grantees Who Spurn Open Access
The Guardian | The Wellcome Trust, the wealthy British medical charity, says it will withhold researchers' final grant payments -- typically 10% of the total -- if they fail to publish their results in open access scientific journals.
Jun 29, 2012
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Data Tsunami: BGI Transfers Genomic Data Across Pacific at Nearly 10 Gigabits/Second
Bio-IT World | During an event in Beijing last week,BGI transferred genomic data across the Pacific Ocean to UC Davis at a sustained rate of almost 10 Gigabits per second, speeds that according to Aspera CEO Michelle Munson mark "the fastest file transfers over public WAN at such distances using commodity hardware.”
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Lawrence Livermore, IBM Offer Petascale Supercomputer to Industry
HPC Wire | The Lawrence Livermore National Laboratory (LLNL) has announced that it is teaming up with IBM to form "Deep Computing Solutions," a collaboration that is being folded into LLNL’s new High Performance Computing Innovation Center (HPCIC).
Jun 29, 2012
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Synthetic Biology's Master Programmers
Technology Review | For more than a decade, synthetic biologists have promised to revolutionize the way we produce fuels, chemicals, and pharmaceuticals. It turns out, however, that programming new life forms is not so easy. Now some of these same scientists are turning back to nature for inspiration.
Jun 28, 2012
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Gates Foundation in Venture Capital Shift
Financial Times | The Gates Foundation plans to take equity stakes in up to a dozen biotech companies this year, signalling a shift towards a “venture capital” approach at the world’s biggest philanthropic organisation.
Jun 27, 2012
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Qiagen Eyes Clinical NGS Market in Acquiring Intelligent Biosystems
Bio-IT World | Intelligent Biosystems (IBS), a privately held next-gen sequencing (NGS) company based in Waltham, Mass., has been acquired by molecular diagnostics company Qiagen, signaling a concerted move to integrate clinical NGS testing into the German company’s diagnostics portfolio.
Jun 26, 2012
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Global Governments' Growing Embrace of Big Pharma
Real Clear Markets | Bill Frezza, a.k.a. author of Bio-IT World's "The Skeptical Outsider" column, pens a scathing dispatch from last week's BIO convention in Boston. "Music, food, and drink abounded, served out of booths with carpets so plush you had to watch your footing. Each was copiously staffed with representatives flown in from around the world busy selling ... well, what? To whom? Using whose money? Toward what end?"
Jun 25, 2012
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Veteran Biotech Investor Kevin Kinsella Talks Genes, Drugs, and Musicals
U-T San Diego | Kevin Kinsella, the veteran San Diego-based biotech investor, is as much about musicals and social networking these days as personalized medicine. "Getting your complete genome sequenced, to find genotypic traits that are going to tell you more about your health? It won’t do us much good, and, frankly, I don’t think people really care.”
Jun 25, 2012
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DNA of Wellderly May Hold Clues to Complex Disease
SF Gate | Scientists are taking a deep look at the genetics of unusually healthy elderly individuals to see if there's something protecting them from common illnesses such as Alzheimer's, cancer, diabetes and heart disease -- or what Eric Topol, director of the Scripps Translational Science Institute, calls "Teflon-coated" genes
Jun 25, 2012
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The (Genomics) View From the 57th Floor
Gigablog | The editors of the journal GigaScience offer their appraisal of the inaugural Bio-IT World Asia conference, held earlier this month in Singapore. "The meeting's proximity to the Singapore Biopolis ... and its location at the 57-story Marina Bay Sands resort (with its rooftop world's highest infinity pool) were a winning combination in getting an impressive mix of scientists from around the Asia-Pacific and beyond... to attend and present."
Jun 25, 2012
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Experts Discuss Future of Medicine at Israeli Presidential Symposium
Jerusalem Post | Experts including USC professor and Navigenics co-founder David Agus discussed topics such as the stagnation in drug development and the future of medicine at the Israeli presidential symposium this week.
Jun 22, 2012
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Cancer, Data and the Fallacy of the $1000 Genome
Forbes.com | In his first "Hacking Healthcare" blog, Jim Golden discusses the central theme of a recent talk by pathologist Mark Boguski. "The time of the $1,000 genome meme is over," he writes. "It served us well for years... but now it is reducing clinical credibility. It’s time for it to leave the lexicon of healthcare; it has to go."
Jun 22, 2012
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Massachusetts Researchers Win $100K Paul Janssen Award
Mass High Tech | Victor Ambros (University of Massachusetts Medical School) and Gary Ruvkun (Massachusetts General Hospital) will share the 2012 $100,000 Dr. Paul Janssen Award for Biomedical Research from Johnson & Johnson for the discovery of microRNAs
Jun 20, 2012
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Toronto’s Hospital for Sick Children Selects Ion Proton in Whole Genome Sequencing Push
Bio-IT World | Toronto's Hospital for Sick Children will feature the Ion Proton sequencer as part of a major push into whole-genome sequencing at a new center for genetic medicine, aiming to sequence up to 10,000 patients annually in the coming years.
Jun 20, 2012
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Open Access is Future of Academic Publishing, says UK Report
The Guardian | "The future lies with open access publishing," says the chair of a new UK report on expanding access to publicly funded research, published this week. "The UK should recognise this change, should embrace it and should find ways of managing it in a measured way."
Jun 20, 2012
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IBM Blue Gene Reclaims Pole Position in TOP500 HPC Rankings
HPC Wire | A 16-PetaFlop IBM Blue Gene/Q computer, Sequoia, has knocked off Japan's K Computer in the latest TOP500 rankings of high-performance computers, released at the International Supercomputing Conference in Hamburg, Germany.
Jun 19, 2012