• The New Cancer Models, Part 3: The Cell Line Critics

    Bio-IT World | Researchers around the world are trying to improve on our laboratory cancer models to better reflect the variable genetic makeup of cancer. In Part 2, we look at the sorry state of cancer cell lines – and a team at Sloan-Kettering who want to improve it.

    Dec 9, 2013

  • 23andMe Suspends Sale of Health Tests

    Bio-IT World | After two contentious weeks of FDA pressure, the last personal genetic testing company to offer health information has at last caved to the regulatory agency's directives, suspending sale of the health-related reports associated with its Personal Genome Service kits.

    Dec 6, 2013

  • Myriad Still Holding Fast on BRCA Patents

    Bio-IT World News Brief | Myriad Genetics has launched a new lawsuit over its ownership of genetic tests for BRCA mutations, this time against Laboratory Corporation of America.

    Dec 5, 2013

  • The Mainstreaming of Human Gene Transfer

    National Academies | Human gene transfer has become so routine in clinical trials that it should no longer merit additional NIH oversight, says a new report from the Institute of Medicine.

    Dec 5, 2013

  • The New Cancer Models, Part 2: A Fly of One's Own

    Bio-IT World | Researchers around the world are trying to improve on our laboratory cancer models to better reflect the variable genetic makeup of cancer. In Part 2, we look at the Mount Sinai Center for Personalized Cancer Therapeutics, where every patient enrolled gets their own line of personalized fruit flies - complete with their unique cancer genes.

    Dec 5, 2013

  • The New Cancer Models, Part 1: The Tumor Organoid Biobank

    Bio-IT World | Researchers around the world are trying to improve on our laboratory cancer models to better reflect the variable genetic makeup of cancer. In Part 1, we look at a Dutch team building a bank of living, miniature organ systems grown from real patients' tumors.

    Dec 4, 2013

  • 23andMe Attracts Class Action

    Bio-IT World News Brief | In the wake of the FDA action halting 23andMe's marketing, a class suit has emerged claiming at least $5 million in damages on behalf of the company's customers.

    Dec 3, 2013

  • Tune in to the Flu Forecast

    Bio-IT World News Brief | This year marks the first real-time use of the flu forecast model developed by researchers at Columbia University's Mailman School of Public Health, which correctly predicted the seasonal influenza peak in 70% of the 108 cities for which forecasts were made.

    Dec 3, 2013

  • The 'Clear Vision' of Claritas Genomics

    Bio-IT World | Claritas Genomics has "a very clear vision to be… the world’s leading provider of next-generation pediatric diagnostics,” according to CEO Patrice Milos. Ten months after splitting off from Boston Children's Hospital, the company is ready to embrace that ambition.

    Dec 3, 2013

  • 23andMe: State of the Debate

    Bio-IT World | FDA’s letter to 23andMe CEO Anne Wojcicki set off a storm of responses ranging from outrage at FDA to disgust with 23andMe. We look at what the letter actually called for, and a survey of the responses in the community.

    Nov 27, 2013

  • Independent Ingenuity

    Bio-IT World | Ingenuity Systems is preparing for the release of a new platform for performing variant analysis in the clinic: a core component of the QIAGEN GeneReader pipeline. Yet like CLC bio, Ingenuity continues to tread an independent path under its new corporate owner.

    Nov 27, 2013

  • Duke Genome Institute to be Broken Apart

    Bio-IT World News Brief | Rumors that the formal structure of the Institute for Genome Sciences and Policy at Duke University will shortly be dismantled have now been confirmed.

    Nov 27, 2013

  • Duke Genome Institute at Hazard

    Duke Check | The Duke Genome Institute may be in peril after a ten-year review, as insiders suggest the Institute will be dismantled and its members relegated to separate departments of the university.

    Nov 27, 2013

  • Room on Campus for Big Data

    Bio-IT World | The Moore and Sloan Foundations are providing a $40 million grant to build university spaces for data science.

    Nov 26, 2013

  • De Novo Protein Modeling With X-ray Lasers

    Bio-IT World News Brief | Using the well-studied enzyme lysozyme as a proof-of-concept, researchers at Stanford's SLAC National Accelerator Laboratory have demonstrated that X-ray laser technology can generate 3D models of unknown proteins without any prior knowledge of their structure.

    Nov 25, 2013

  • FDA to 23andMe: Stop Marketing Kits Immediately

    Bio-IT World | The Food and Drug Administration issued a warning letter to 23andMe CEO Anne Wojcicki on Friday, demanding that the company "immediately discontinue marketing the [Personal Genome Service]."

    Nov 25, 2013

  • Oxford Nanopore Calls for Early Access Program Applicants

    Bio-IT World News Brief | Oxford Nanopore this morning invited registration for the MinION Access Programme (MAP). Registration will remain open through the holiday period, the company said. In early 2014, at least two days notice will be given of closure of the registration period. Preference will not be given to early applicants.

    Nov 25, 2013

  • The Druggable Genome Is Now Googleable

    Bio-IT World | Twin brothers Obi and Malachi Griffith have developed a free online database, the Drug Gene Interaction Database at dgidb.org, where researchers can quickly sort through the known drug interactions in the human genome.

    Nov 22, 2013

  • CLC bio Stays the Course

    Bio-IT World | CLC bio, the world’s largest software developer for first-tier analysis of raw sequencing data, was recently acquired by QIAGEN and swept into a sequencing-to-informatics pipeline built around the still-unreleased GeneReader instrument. Big changes for this industry leader? Perhaps not.

    Nov 20, 2013

  • Frederick Sanger Dies, 95

    BBC | Frederick Sanger, two-time winner of the Nobel Prize and considered the "father of genomics", has died at the age of 95.

    Nov 20, 2013