• PacBio Releases New Chemistry

    Bio-IT World News Brief | Pacific Biosciences, maker of the RSII sequencing instrument, has launched a new reagent kit to boost both the throughput and read length of its sequencers.

    Oct 16, 2014

  • 2015 Bio-IT World Best Practices Call for Entries Is Open

    Bio-IT World | Bio-IT World is now seeking entries for the 2015 Bio-IT World Best Practices competition, an awards program that for eleven years has highlighted technology innovations to enable drug discovery, biomedical research, and the practice of medicine.

    Oct 15, 2014

  • The Next Generation of DNA Vaccines Is Poised to Transform the Healthcare Landscape

    Bio-IT World | Contributed Commentary | Teri Heiland argues that advances in vaccine delivery and vector design are paving the way to safe and effective nucleic acid vaccines, which could be used against pathogens, allergies, autoimmune disease and in the growing field of cancer immunotherapy.

    Oct 13, 2014

  • Cell Culture Model of Alzheimer's First to Recapitulate Key Physiology

    Bio-IT World News Brief | A new model of Alzheimer's disease, created at the Genetics and Aging Research Unit of Massachusetts General Hospital, is the first to recreate both the "plaques" and the "tangles" that the amyloid hypothesis predicts are central to the disease's symptoms.

    Oct 13, 2014

  • Copy Number Variants in Neurological Disease

    Pacific Standard | More reliable methods for detecting large copy number variants across the whole genome are helping to reveal the importance of these mutations in explaining neurological disorders.

    Oct 10, 2014

  • Roche Purchases AbVitro's DNA Enrichment Technology for Clinical Samples

    Bio-IT World News Brief | Roche, which has been retooling its next generation sequencing strategy since beginning the closure of 454 Life Sciences last October, has acquired a new sample preparation technology for an NGS pipeline.

    Oct 10, 2014

  • Illumina Opens BaseSpace to Proteomics Data

    Bio-IT World | The OneOmics Project, a partnership between Illumina and mass spectrometry provider AB SCIEX, has produced a network of apps in the BaseSpace cloud informatics environment to store and analyze mass spec and proteomics data, the first multi-omics functions in Illumina's flagship analytics project.

    Oct 8, 2014

  • BRCA2 Protein Structure Described

    Imperial College London News | The BRCA1 and BRCA2 genes are well known for mutations that raise the risk of developing breast cancer, but their structure, and the mechanisms by which healthy copies of these proteins repair broken DNA strands, have been little understood.

    Oct 7, 2014

  • Nobel Prize Awarded for Decoding Geometrical Pattern of Brain's Spatial Awareness

    Nature News | Norwegian neuroscientists May-Britt and Edvard Moser today received the 2014 Nobel Prize in Physiology or Medicine, along with former supervisor John O'Keefe, for their discovery of "grid cells" in the brain's entorhinal cortex.

    Oct 6, 2014

  • FDA Issues Draft Guidance on Laboratory Developed Tests

    Bio-IT World News Brief | Today, the FDA officially issued a pair of draft guidance documents outlining its regulatory plans for laboratory developed tests.

    Oct 3, 2014

  • September News and Product Briefs

    Bio-IT World | News and product releases from around the industry, including early-stage pharma startups supported by GSK and Avalon Ventures, and the Eaglecore cloud knowledge management platform.

    Oct 2, 2014

  • TranSMART Platform Powers International Asthma Research Initiative

    Bio-IT World | The U-BIOPRED Consortium, an international project searching for novel biomarkers to better define severe asthma cases, received a Bio-IT World Best Practices Award this spring for its far-reaching implementation of the tranSMART knowledge management platform.

    Oct 1, 2014

  • First NIH Grant Awards in BRAIN Initiative

    Bio-IT World News Brief | This morning, the NIH announced the recipients of its first round of grants tied to the nationwide BRAIN Initiative, totaling $46 million in funding for research meant to develop an integrated understanding of human brain function.

    Sep 30, 2014

  • New, Larger Facility for Transcriptic Robotics Lab

    Bio-IT World News Brief | Transcriptic, the programmable lab-for-hire, has moved to a new, 10,000-square foot location as it adds more instruments and "work cells" where experiments are conducted.

    Sep 29, 2014

  • CRISPR Knockin Mice Enable Rapid Gene Editing

    Bio-IT World News Brief | Researchers at the Broad Institute of MIT and Harvard have created a line of mice whose cells naturally express the Cas9 protein used in CRISPR gene editing, which can be used for virtually any gene knockdown experiment.

    Sep 26, 2014

  • GeneHub Pulls Its Kickstarter Project to Sequence Whole Genomes for the Masses

    Bio-IT World News Brief | Just two days after launching a Kickstarter campaign to start the world's first brokerage service for personal whole genome sequencing, GeneHub has pulled the plug.

    Sep 25, 2014

  • Illumina at EmTech

    Bio-IT World News Brief | Francis de Souza, president of gene sequencing company Illumina, spoke at the EmTech conference in Cambridge this week about his company's pivot to clinical use, and a growing market for whole genome sequencing that he says will produce 228,000 whole human genomes in 2014 alone.

    Sep 25, 2014

  • GeneHub Wants to Sell Whole Genomes Direct to Consumer

    Bio-IT World News Brief | San Francisco-based GeneHub has plans to become the first company selling whole genome sequences to all comers, and launched a Kickstarter campaign this week to raise the funds it needs to get started.

    Sep 24, 2014

  • Big Changes for Molecular Diagnostics as FDA Moves on Lab Developed Tests

    Clinical Informatics News | As the FDA extends its oversight to tests designed and performed in a single laboratory, diagnostic companies are celebrating a more even playing field. But hospital and academic labs worry that the high price tag of FDA review will stifle their in-house tests without protecting patients.

    Sep 23, 2014

  • 15 Biotechs to Watch

    Fierce Biotech | Fierce Biotech has unveiled its hotly-anticipated Fierce 15, an annual list of biotech companies showing special promise in delivering transformative new therapies.

    Sep 22, 2014