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Low-Bass Music Controls Insulin Release From Designer Cells
Bio-IT World| Scientists in Switzerland have figured out how to remotely control genes in a way that could one day enable diabetics to produce and administer insulin directly in their body rather than relying on injections, inhalers, and pumps. Low-bass heavy popular music and movie soundtracks are being used to trigger insulin release from designer cells in implantable capsules when intentionally directed at the implant site.
Oct 11, 2023
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Proteomics Enables Vastly Improved Cardiovascular Disease Prediction
Bio-IT World| The rise and fall of blood protein levels over time is an astonishingly good way to assess the risk of major atherosclerotic cardiovascular disease (ASCVD) events such as myocardial infarction (heart attack), as well as an ideal biomarker of the progression of disease and its regression in response to treatment.
Oct 10, 2023
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Children’s Mercy Brings Long Read Sequencing to Clinical Care
Bio-IT World Beginning today, the research team at Children’s Mercy Kansas City is bringing long read sequencing to clinical care, following three years of research and testing of PacBio HiFi sequencing. The transition is expected to speed the diagnostics odyssey for critically ill patients and their families.
Oct 6, 2023
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Synthace’s ‘Design of Experiments’ Approach Enables Multi-Factorial Wet Lab Experiments
Bio-IT World| INNOVATIVE PRACTICES AWARDS—Cultured meat may not be the standard use case for a Bio-IT World Innovative Practices Award, but the entry from Higher Steaks and Synthace caught the judges’ attention less for its application as for the innovation in experimental design.
Oct 4, 2023
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Bio-IT World Issues 2024 Innovative Practices Awards Call for Entries
Bio-IT World| Bio-IT World is accepting entries for the 2024 Innovative Practices Awards, a competition designed to recognize the most exciting partnerships and projects pushing the life sciences industry forward.
Oct 3, 2023
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Chan Zuckerberg Life Sciences Computing System, Microsoft and Paige AI Partnership, Rehm Takes Chair of GA4GH
Bio-IT World| Paige and Microsoft aim to build the world’s largest image-based AI models for digital pathology and oncology; Flatiron Health and FDA partner; HHS extends partnership with Regeneron; the GA4GH Board of Directors has elected Heidi Rehm to succeed Ewan Birney; and more.
Sep 28, 2023
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Follow the Money: NIH Establishes “Multi-Omics” Data Research Center, Huge Funding for Advancing AI Platform
Bio-IT World| Moderna and Immatics launch a strategic research and development collaboration to pioneer novel and transformative therapies for cancer patients with high unmet medical need; The National Institutes of Health is establishing the Multi-Omics for Health and Disease Consortium to advance the generation and analysis of “multi-omic” data for human health research; Generate:Biomedicines has secured huge funding to advance its AI platform used to increase precision, speed, and probability of success of novel therapeutics; more.
Sep 27, 2023
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The Why, How, and Hope of Generative AI and Data Technology With Bryn Roberts
Bio-IT World| As artificial intelligence continues to rapidly develop, it is tempting for organizations to rush into using AI—or at least an AI buzzword. In the latest episode of the Trends from the Trenches podcast, host Stan Gloss channels Simon Sinek and challenges Bryn Roberts to start with why.
Sep 26, 2023
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Proteomics-Based Assays To Enable Precision Medicine For Ovarian Cancer
Bio-IT World | Over 900 genes have been implicated in the resistance of tumors to platinum-based chemotherapy that map to many different cellular pathways, thwarting efforts to identify a biomarker to predict refractoriness.
Sep 21, 2023
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Study Ties Body Mass Index To Size Of The Hypothalamus
Bio-IT World | The brain structure of people with higher body mass index (BMI) looks quite different than individuals of a healthy weight, based on MRI scans of their hypothalamus analyzed with a recently developed machine learning algorithm.
Sep 20, 2023
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City of Hope’s Harmonized, Findable, Accessible Precision Medicine Data Platform
Bio-IT World | INNOVATIVE PRACTICES AWARDS—When City of Hope wanted to better use its primary and secondary clinical research data and harmonize files on more than 700,000 patients so they were findable and accessible, the hospital built a highly scalable, compliant cloud-based platform.
Sep 19, 2023
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Cross-Department Collaboration Reveals Business Intelligence Already On Hand
Bio-IT World | INNOVATIVE PRACTICES AWARDS—There are questions every research group could ask. At Regeneron’s Research and Preclinical department, tackling these questions meant accounting for more than 2,000 expensive and space-constrained instruments and seeking insight into how they are used.
Sep 14, 2023
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COVID Vaccine Developers May Want To Pivot To Symptom Prevention
Bio-IT World | Vaccine developers may want to consider designing formulations intended to prevent symptoms rather than infection, which the COVID-19 pandemic has demonstrated can be hard to do with any long-lasting effect.
Sep 13, 2023
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Study Finds Breast Cancer Spreads During Sleep, Highlights Role Of Hormones
Bio-IT World | The recent discovery that the metastatic spread of breast cancer accelerates during sleep sparked a lively conversation at last month’s Next Generation Dx Summit about new paths of exploration for thwarting a deadly pan-cancer process claiming 12 lives worldwide every minute.
Sep 12, 2023
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Scaling R&D Drug Discovery: The Future Of Lab Automation
Bio-IT World | In the coming decades, many of the grand challenges that society faces, from global food shortages to disease control and climate change, has the opportunity to be solved by biology. To achieve this, we must enable researchers within the biotech and healthcare ecosystems to be more productive than ever by improving scale, reproducibility, and accessibility.
Sep 8, 2023
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Illumina Names Jacob Thaysen of Agilent New CEO
Bio-IT World | Illumina today announced that its Board of Directors has appointed Jacob Thaysen, Ph.D., senior vice president of Agilent Technologies and president of its Life Sciences and Applied Markets Group, as Illumina’s next Chief Executive Officer, effective September 25, 2023.
Sep 5, 2023
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Novel Biomarker Tracks Tightly With Tau Tangles In Alzheimer’s Disease
Bio-IT World | Researchers in the U.S. and Sweden have identified a biomarker (MTBR-tau243) for Alzheimer’s disease that tracks with the amount of damaging tau tangles in the brain and, when combined with a specific phosphorylated tau species (p-tau205), is nearly as predictive of cognitive function as tau-positron emission tomography (tau-PET) imaging.
Sep 5, 2023
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Nanopore News from Oxford Nanopore, University of Missouri, New Genedata Product, More
Bio-IT World | University of Missouri researchers developed an innovative method using nanopores; Oxford Nanopore speeds basecalling for MinKNOW; Standigm and Nashville Biosciences partner on early drug discovery research, and more.
Aug 31, 2023
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The First Commercial-Scale IDMO Smart Factory, Company Advancements, RNA Editing Platforms, More
Bio-IT World | Cellares will use funding to launch the world’s first commercial-scale IDMO Smart Factory; Genesis Therapeutics plans to use Series B financing to elevate into a clinical stage company and further invest in its AI platform; Amber Bio will use funds to advance first-of-its-kind RNA editing platform; more.
Aug 30, 2023
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The Future of Innovation, Generative AI, and More with Jeanne Kehren
Bio-IT World | When the first human genome was sequenced, Jeanne Kehren switched from veterinary medicine to the pharmaceutical industry. After that “magical moment of hope,” Kehren and her colleagues looked forward to a bright future for individualized medicine and treatment.
Aug 29, 2023