Kroger Health Establishes Clinical Trial Site Network to Increase Reach and Access to Research Studies

CINCINNATI, Jan. 24, 2023: Kroger Health, the healthcare division of The Kroger Co. (NYSE: KR), today announced the establishment of its clinical trial site network in conjunction with pharmaceutical industry sponsors, contract research organizations, and health systems. The announcement comes with Kroger's first trial in active recruitment for colorectal cancer gut and immune health observation.

In collaboration with Persephone Biosciences, Kroger Health is actively recruiting for the ARGONAUT clinical study (NCT04638751) to identify microbiome-based biomarkers indicative of colorectal cancer. Beginning in the Toledo, Ohio area, select Kroger pharmacies and its affiliate, The Little Clinic LLC, locations will enroll its initial cohort of 55 people with a variety of colorectal cancer risk levels to advance the understanding of gut and immune health. During the next year, Kroger Health plans to enroll additional participants and increase its locations.

"With our team of more than 24,000 healthcare professionals, under the umbrella of America's grocer, we are positioned at the nexus of food and healthcare, which provides us with the unique opportunity to increase accessibility to clinical trial opportunities," said Colleen Lindholz, Kroger Health president. "As a trusted community healthcare destination, we envision a future where our work transforms the clinical trial landscape and provides expanded trial access to the people we serve."

According to the CDC, of cancers that affect both men and women, colorectal cancer is a leading cancer killer in the US¹. It has been proven that colorectal cancer screening saves lives. Approximately nine out of 10 people whose colorectal cancers are found early and treated appropriately are still alive five years later².

Kroger Health is seeking participants with the following risk factors:

Age 45 and older who need their standard of care colonoscopy
Age 18 or older with one or more first-degree relatives with a history of colorectal cancer
Those who have had three or more polyps found during a colonoscopy or who have a personal history of colorectal cancer

A growing body of evidence shows the bacteria living in the gut may influence an individual's risk to develop colorectal cancer. The data collected from this trial will be used to develop personalized medicines and find cancer-specific indicators that may help guide future treatment and preventive strategies, such as utilizing food as medicine.

Ninety percent of the U.S. population lives within five miles of a pharmacy³, and fifty-one percent of all Kroger stores are located in socially vulnerable areas. With select Kroger pharmacies and Little Clinics now serving as clinical trial sites, America's grocer is expanding its commitment to healthcare by creating research opportunities in the communities where customers live, work and eat. Alongside the grocer's data analytic capabilities from, Kroger Health is able to engage a wider range of the population in clinical trials. Digital tools, virtual care visits and personalized communication will facilitate patient retention throughout the study's lifecycle. In addition, its clinics, dietitians, pharmacy services, and relationships with other healthcare organizations enable Kroger Health to offer end-to-end clinical trial management within a variety of preventive and therapeutic areas.

"Through our collaborations with health systems across the country, we can nimbly work to optimize the patient experience to improve healthcare delivery and maintain continuity of care while expanding the frontiers of care and treatment," said Jim Kirby, PharmD, chief commercial officer of Kroger Health. "This is the first of many clinical trial opportunities that will utilize us as an alternative to the traditional clinical trial and research organization model."

People interested in participating in the ARGONAUT study can call 1.833.317.0661 for more information on qualifications and study background.

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About Kroger
At The Kroger Co. (NYSE: KR), we are dedicated to our Purpose: To Feed the Human Spirit™. We are, across our family of companies nearly half a million associates who serve over 11 million customers daily through a seamless digital shopping experience and retail food stores under a variety of banner names, serving America through food inspiration and uplift, and creating #ZeroHungerZeroWaste communities by 2025. To learn more about us, visit our newsroom and investor relations site.

About Kroger Health:
Kroger Health, the healthcare division of The Kroger Co., is one of America's leading retail healthcare organizations. Kroger Health and the Kroger Family of Pharmacies and clinics operate more than 2,200 pharmacies and 226 clinics in 35 states serving more than 17 million customers annually. Our team of 24,000 healthcare practitioners, including pharmacists, nurse practitioners, dietitians and technicians, believe in practicing at the top of our licenses, enabling "food as medicine" to help prevent disease before it starts, and helping people live healthier lives. For more information, visit www.kroger.com/health.

About ARGONAUT:
The official title of the ARGONAUT study is: "Development and Analysis of a Blood and Stool Sample Bank for Cancer Patients, Enabling the Systematic Study of the Effect of Blood and Gut Microbiomes on Response to Treatment." More information can be found at https://www.clinicaltrials.gov/ using the identifier NCT04638751.

Centers for Disease Control and Prevention, Colorectal Cancer Statistics, Colorectal Cancer Statistics | CDC Colorectal Cancer Statistics | CDC
Centers for Disease Control and Prevention, Basic Information about Colorectal Cancer | CDC Basic Information About Colorectal Cancer | CDC
Strand MA, Bratberg J, Eukel H, Hardy M, Williams C. Community Pharmacists' Contributions to Disease Management During the COVID-19 Pandemic. [Erratum appears in Prev Chronic Dis 2020;17. http://www.cdc.gov/pcd/issues/2020/20_0317e.htm.] Prev Chronic Dis 2020;17:200317. DOI: http://dx.doi.org/10.5888/pcd17.200317external icon