A Robust Telomere Aging Clocks Platform Helps Conduct Lab-Grade Telomere Length Analysis

New York, United States—Oct 19, 2022—A robust telomere aging clocks system combined with RF, qPCR, STELA, and TESLA techniques is newly reconfigured to conduct specialized lab-grade telomere length analysis and offer comprehensive pictures of biological aging.

“With our integrated telomere aging clocks platform, researchers can utilize simple, fast, and scalable measurement to achieve real-time and high-throughput detection of classical telomere length as well as absolute telomere length and distribution. Consequently, telomere-associated modifications can be used as biomarkers for aging studies and disease research,” said an expert engaged in the establishment of the telomere aging clocks platform.

Telomeres are sections of genetic material at the end of each chromosome whose primary function is to prevent chromosomal ‘fraying’ during cell replication. Studies suggest that the length of telomere can be used in revealing the cellular aging process and discovering factors that may contribute to aging diseases. To accurately measure telomere length, a variety of techniques, e.g., RF, qPCR, STELA, and TESLA, are developed as the foundation of this robust telomere aging clocks platform.

The telomere length aging clocks technology adapted the most advanced tools available to achieve comprehensive telomere analysis, like average telomere length, shortest telomere length, absolute telomere length, and telomere distribution. This platform enables individual telomere tests to run in a high-throughput and low reagent consumption way. In addition, serial evaluation of telomere length can rapidly differentiate the aging of one relative to the normal population and provide valuable clinical information for various conditions, such as myelodysplastic syndromes, acute myeloid leukemia, and liver failure.

In addition, the PCR-based platform can take part in the donor selection and screening process before bone marrow or stem cell transplantation. Therapies directed at slowing the loss of telomere length may also slow aging and age-related diseases.

Furthermore, the telomere length aging clocks can offer the information needed for smart lifestyles that improve health and longevity. Essentially, anyone who wants a peek at their telomeres to get hard data on how the body is aging is a great candidate for telomere assay. Nevertheless, the Telomere assay can also identify risk factors for cancer, heart disease, metabolic disease, cognitive impairment, and more.

About Telomere Length Aging Clocks Platform

The telomere length aging clocks platform includes a variety of aging clock technologies with multiple complementary approaches that allow researchers to access diverse levels of aging exploration. This technology can provide a safe, efficient, and convenient way to measure and analyze telomere length and uncover underlying mechanisms interconnecting telomere length distribution to telomere maintenance and biological aging.