Temedica Introduces Permea: First Analytics Platform Integrating Patient-Generated Health Data

PRESS RELEASE

Temedica Introduces Permea: First Analytics Platform Integrating Patient-Generated Health Data

• Unique real-world data platform integrating proprietary, regulatory-grade,
patient-generated health data
• Permea translates previously inaccessible data into knowledge to provide
new medical and scientific insight for stakeholders along the healthcare
value chain
• Permea addresses USD 57 billion real-world evidence market potential with
two new collaboration models: Permea Insights and Permea Monitor
• All Permea operations comply with the German laws on data protection and
security (GDPR)

Munich, Germany, January 12, 2022 – Temedica GmbH, a leading digital health and
data analytics company, today announces the launch of Permea. Permea is a unique
platform providing medically sound analyses and actionable insights to a whole
range of questions and challenges arising along the value chain in the healthcare
market. By combining regulatory-grade, patient-generated data with a variety of
readily available scientific and commercial data sources for the first time, Permea
provides new insights into therapies and their effects under real-world conditions.

Permea supports biopharma, biotech, and medtech companies, physicians,
regulatory authorities, payers, and patients in making knowledge-based decisions
for improving therapeutic options. The platform combines, structures, and analyzes
data from multiple sources, including proprietary longitudinal patient-generated
data from digital health apps and wearables, scientific publications, and prescription
data. Permea can uncover the most effective therapy for a defined cohort, identify
reasons for a therapy change, and improve current healthcare treatment with new
insights. In addition, the platform expands the data provided by clinical trials and
supports the planning of new studies. Permea enables more highly informed
decisions for new strategies in research and development, regulatory approvals,
market launches, and commercialization of therapies. Patients benefit from new
knowledge and information on their individual disease progression.

Dr. Benjamin Friedrich, Chief Medical Officer of Temedica, said:

“For the first time, patient-generated data from millions of patients is
intelligently combined with other medically relevant data and transformed into
applicable knowledge. In this way, we bring the personal experience of patients
into real-world evidence analyses. This makes Permea an indispensable and
pioneering technology for multiple challenges in the healthcare market. Permea
reveals the real stories behind patient data and statistics and is therefore
essential for the digital future of personalized medicine."

Gloria Seibert, Founder & Chief Executive Officer at Temedica, added:

"The launch of Permea is a fundamental step for achieving Temedica’s vision in
personalized medicine and opens a billion-dollar market opportunity in realworld
evidence. Our technology platform, which leverages unique proprietary
data and processes, enables us to form novel alliances with healthcare
companies and provides critical momentum to improve care and everyday
support for patients around the world. Permea is already delivering valuable
insights for informed decision making in therapy development. The initial
feedback received from clients and partners is highly encouraging."

With Permea Insights and Permea Monitor, Temedica currently offers clients two
distinct cooperation models:

Permea Insights answers specific questions and provides analytics in the form of
customized reports. Permea Insights helps clients better understand patient needs
and how therapies and patient behavior influence the entire patient journey. To do
this, Permea uses technologies such as machine learning and artificial intelligence.
The underlying algorithms enable the integration of multiple data sources in real
time. Clients receive tailored analytics and reports to make knowledge-based
decisions.

Permea Monitor enables clients to independently perform analyses with Permea
datasets and combine them with their own knowledge and data pools. This is based
on innovative data science methods and artificial intelligence, embedded in an
intuitive user interface. Each Permea Monitor is configured according to specific
client needs and provides the data and insights that are crucial for their purposes.

Permea can also optimize clinical trial planning by providing information about the
potential therapy effect in defined patient cohorts and can be used for optimization
of study planning. Potential for further development and optimization of therapies
can be uncovered by showing new correlations of therapy success, cohorts, and
symptoms. Analysis of the data may uncover motivations for therapy changes and
disease burden, making the platform critical for strategic and trial design planning.

Permea uses long-term historical data from millions of patients to identify
characteristics, correlations, anomalies, and differences between patient
populations under real-world conditions. Temedica also uses the information
obtained through Permea for its digital health apps—the patient companions—
thereby offering patients personalized support with individual recommendations.

All international Permea offerings are compliant with the General Data Protection
Regulation (GDPR). In generating and processing data, Temedica meets all data
protection and security requirements and attaches great importance to
transparency towards all stakeholders.

About Permea

Permea is a new offering from Temedica available to different stakeholders in the healthcare space.
Permea combines multiple data sources, including longitudinal, patient-generated data with high
resolution related to time, geography and patient cohorts. Its customizable solutions provide insights
on various questions and challenges along the health care value chain, including research and
development, regulatory approvals, market launches and commercialization of therapies. The Permea
Insights and Permea Monitor offerings provide in-depth knowledge about therapies and their effects
under real-world conditions, enabling more highly informed decisions. Based on artificial intelligence
and innovative algorithms, Permea provides answers to industry relevant questions. All Permea
operations comply with the General Data Protection Regulation (GDPR) laws on data protection and
security and meet the high standards also internationally. For more information, please visit
www.permea-health.com.

About Temedica GmbH

Temedica is a Munich, Germany-based digital health company with a mission to bring the patient into
the center of healthcare. The company develops state-of-the-art digital patient companions for
complex, chronic conditions. These apps support patients with personalized guidance and help them
navigate through healthcare systems by considering their individual needs. Through direct and longterm
interaction with patients, Temedica generates unique and previously unknown real-world
evidence about disease progression and the individual effectiveness of therapies. Temedica has an
expertise in the personalized support of patients as well as in compiling, structuring and analyzing
respective health data. Its data analytics platform Permea is designed to enable unique insights along
the entire healthcare value chain and patient journey. Temedica is supported by a consortium of
renowned investors with longstanding track-records in the biopharmaceutical industry, including the
founding investors of BioNTech. Further information is available at https://temedica.com/en/.

For further information please contact:
Temedica GmbH
Dr. Benjamin Friedrich, CMO
T +49-89-215544-970
Email: benjamin.friedrich@permea-health.com

International Media and IR Contact
Dr. Brigitte Keller, Katja Arnold
T +49 89 210228 0
UK: Shaun Brown
M: +44 7867 515 918
Email: temedica@mc-services.eu