Creative Biolabs Provides Anti-Human CXCL12 Therapeutic Antibody for Research Use

SHIRLEY, NY - Jan 12, 2020 - January 12, 2020, Creative Biolabs, as a leading supplier in the recombinant antibody (rAb) discovery and manufacturing, announced the newly-developed product CXCL12 for research use. With the help of professional scientists in Creative Biolabs, Creative Biolabs is able to provide more high-quality products and professional services for clients from different scientific eras all over the world. Since its establishment, Creative Biolabs has been known among consumers for its high quality services. And of course, it is always upholding faith of “providing high-quality and professional services for customers.”

The main role of chemokines is the migration of chemokine cells, and the cells migrate to the source of chemokine along the signal that the concentration of chemokine increases. Some chemokines control immune cell chemotaxis during immune monitoring. For example, induce lymphocytes to lymph nodes. Chemokines in these lymph nodes see the invasion of pathogens through the interaction of antigen presenting cells in these tissues. These are called homeostasis chemokines, and they are produced without stimulation. Some chemokines play a role in development; they can stimulate the formation of new blood vessels; they provide specific key signals to promote the formation of cells. Other chemokines can be formed by a variety of cells in response to cell infections and viral infections; they can also be caused by non-infectious stimuli such as inhalation of silicon dioxide, urinary tract stones, and the like.

cxcl12 antibody and its receptors play important roles in many physiological and pathological processes. Changes in intracellular signals occur in tumors through several different pathways. It can promote tumor cell proliferation, movement, adhesion, invasion and secretion, etc., and affect the occurrence, development and prognosis of tumors.

“the newly-developed product will be a milestone of Creative Biolabs and it will bring great affect to the market. In order to providing the qualified and high-quality cxcl12 antibody, our scientists have repeatedly tested its performance. Predictably, it works well and is qualified to meet customers’ demands. cxcl12 plays very important roles in the different body areas, including central nervous system, bone marrow, heart and lymphatic transport.”said Dr. Bruce, senior scientist in R&D of Creative Biolabs.

The CXCL12/CXCR4 axis not only plays a role in chemotaxis and cell migration, but also participates in a variety of life activities such as cell proliferation, differentiation, homing of stem cells, inflammatory response, immune regulation, endocrine regulation and improvement of pain sensitivity. CXCR4 is highly expressed in many types of tumors, and has a significant effect on promoting distant metastasis of these types of tumors. In terms of stem cell homing, the expression of CXCR4 in mesenchymal stem cells is generally not high. CXCR4 is overexpressed in mesenchymal stem cells through viral vectors. It has been used for transplantation to treat injury or inflammatory diseases. It has achieved very good results and caused widespread attention. In terms of immune regulation, researchers have found that the CXCL12 / CXCR4 axis is also involved.

About Creative Biolabs

With more than ten-year experience in providing products and services in recombinant antibody fields, Creative Biolabs has gained a good fame among customers. It is believed that more and more high-quality products will be developed by Creative Biolabs.