Creative Biolabs Released the Unmatchable Diabody for Clinical Use

SHIRLEY, NY - Oct 23, 2018 - Oct 22, 2018, as an unchallenged experience in antibody production, Creative Biolabs is always holding the faith of providing high-quality products and services to clients all over the world. Recently, it released the diabody with high affinity and low immunogenicity for academic and clinical use.  

Diabody, the recombinant bispecific antibody, is constructed from heterogeneous single-chain antibody. Generally speaking, diabodies have been prepared from bacterial periplasmic fraction by using a co-expression vector. As a model, construction of a diabody reactive with both the adenocarcinoma-associated antigen MUC1 and the CD3 molecule on T cells (Mx3 diabody) was studied. With regard to recombinant BsAb, diabodies or dimeric antibody fragments consisting of two non-covalently associated single-chain antibodies have attracted particular attention.

“Diabodies from Creative Biolabs are comprised of two chains expressed separately as usual. With well-experienced scientists and advanced platforms, Creative Biolabs is capable of providing customers diabody with high affinity and low immunogenicity. Due to the capability of simultaneously binding to two different proteins and being rigid enough to be crystallized, diabodies are attractive candidates for mediators in assembling protein nano-structures. And recently, diabodies are being actively studied because their “two-target” functionality can improve the therapeutic value of the individual antibodies by causing hetero-dimerization of antigens.” said Dr. Britt, a senior scientist in R&D of Creative Biolabs.

“What’s more, over nearly a half year of studying our diabody, our scientists distributed a lot to make sure the high quality of diabodies. So we can guarantee the practicality of diabody to customers. With more than ten years of experiences in antibody production, we have gained a good fame among clients and the field of antibody companies. So we are able to serve more customers in all over the world. Additionally, we want to serve more researchers from life science research field. ” Dr. Britt added.

More detailed information about our diabody, customers can find more professional description on the website. Some other products, such as minibody antibody, biosimilar monoclonal antibodies can also be

About Creative Biolabs

As an excellent supplier and manufacturer in the field of antibody production, Creative Biolabs is able to produce more high-quality products and services with its cutting-edge hybridoma development and phage display platforms. More than ten-year of specificity in antibody production, Creative Biolabs is capable of offering products ranging from antibody / peptide libraries, Biosimilar cell lines, Chimeric antigen receptor (CAR) products, antibody-drug conjugates (ADCs) to engineered antibodies.