View Press Releases
PREMIER Biosoft announces the release of SimGlycan® Enterprise Edition 5.0 to support automated mass spectrometry glycan quantitation analysis using Thermo Scientific™ aminoxyTMT™ Reagents
PALO ALTO, CA - Jun 11, 2014 - Palo Alto, California -: PREMIER Biosoft, a next generation leader in bioinformatics, today announced the release of Enterprise Edition of SimGlycan® v. 5.0, a comprehensive high throughput tool to provide support for glycan quantitation using Thermo Scientific aminoxyTMT for MS/MS glycan data analysis workflows. Additionally, it can be used for processing of LC-MS data for peak detection, peak picking and alignment of glycans based on retention time, precursor m/z values and observed intensities across multiple samples.
The Thermo Scientific aminoxyTMT reagents are designed
to provide efficient relative quantitation of carbohydrates,
improve labeled-glycan ionization efficiency and increase
analytical throughput. These reagents can be used for quantitative
analysis of native N-glycans by direct or LC-coupled ESI-MS. Using
SimGlycan®, glycans are quantified by measuring reporter ion peak
intensities from the corresponding MS/MS spectra. Various
charts are provided to facilitate visualization of either the
quantity of each glycan in different TMT channels or relative
change in abundance of glycans across samples.
According to Julian Saba, Senior Scientist, life science mass
spectrometry at Thermo Fisher Scientific, " One of the major new
application areas of TMT reagents, until now being used for protein
quantitation, is quantitative profiling of glycan isoforms and
discovery of glycan biomarkers. PREMIER Biosoft's SimGlycan®
is designed to ably provide the informatics support needed for
analyzing the data generated by this workflow. "
"The lack of informatics tools to automate the qualitative and quantitative analysis protocols till now remained a major challenge. The functionality now introduced in SimGlycan® is a major step towards narrowing the existing data analysis gaps. We are now offering the research community an effective tool for data validation, visualization and quantitation," said Arun Apte, CEO at PREMIER Biosoft.
About PREMIER Biosoft
Founded in 1994, is a group of computer scientists and biologists
dedicated to producing cutting edge intuitive software for research
in life sciences. Our goal is to study the most recent innovations
in life sciences and translate them into software products to aid
research.
More information is available at: http://www.premierbiosoft.com.
Contact:
Shonali Paul
PREMIER Biosoft
650-856-2703
http://www.premierbiosoft.com