• Big Pharma, Moderna on An AI-Empowered Era of Drug Discovery

    Bio-IT World | In January, Heidi Rehm will take over the leadership of the Global Alliance for Genomics and Health, GA4GH, replacing out-going Chair Ewan Birney. Rehm sat down with Stan Gloss to talk about the mission of GA4GH and share areas of future focus for the latest episode of the Trends from the Trenches podcast.

    Nov 8, 2023

  • ‘Subway Map’ Approach To Finding Targeted Therapeutics For Lyme Disease

    Bio-IT World | Scientists in Boston are flipping the script on the current antibiotic development paradigm by painstakingly choosing a good metabolic target for combatting Lyme disease. The typical approach has been to test vast numbers of chemicals against the culprit bacteria rather than design a compound to specifically go after one of its essential biological activities.

    Nov 7, 2023

  • The Promising Future of AI in Synthetic Biology

    Bio-IT World | The synthetic biology landscape has evolved considerably to include new ways of accessing DNA for research and therapeutic development. An important advance is that DNA production is no longer limited to third-party suppliers.

    Nov 3, 2023

  • Dementia-Associated Protein Provides Clues About Preeclampsia

    Bio-IT World | Researchers at the University of Western Ontario and Brown University were surprised to discover an “almost identical mechanism” appearing in the blood and placenta of women with preeclampsia as has been previously found in the brains of older individuals with Alzheimer’s disease (AD), traumatic brain injury (TBI), and vascular dementia.

    Nov 1, 2023

  • New Chair, Heidi Rehm, on the Future Focus of the Global Alliance for Genomics and Health

    Bio-IT World | In January, Heidi Rehm will take over the leadership of the Global Alliance for Genomics and Health, GA4GH, replacing out-going Chair Ewan Birney. Rehm sat down with Stan Gloss to talk about the mission of GA4GH and share areas of future focus for the latest episode of the Trends from the Trenches podcast.

    Oct 31, 2023

  • Enkelejda Miho on Curiosity, Courage, and Advancing Research With Adisciplinary Approaches

    Bio-IT World | In the latest episode of The Chain podcast, host Ben Hackel, Professor of Chemical Engineering & Materials Science at the University of Minnesota, speaks with Enkelejda “Ledi” Miho, Professor of Digital Life Sciences at the University of Applied Sciences Northwestern Switzerland FHNW, about the data challenges currently facing drug discovery, and how an adisciplinary approach would allow a more fruitful flow of ideas between indication silos, fueling discovery.

    Oct 27, 2023

  • NTT Corporation Joins Japan Precision Medicine Platform Project, FDA Gives Grant To Aspen Neuroscience, Cancer Research Horizons And Genialis Team Up

    Bio-IT World | NTT Corporation joins an agreement with BC Platforms AG, PRIME-R, and Bioxcellerator to develop the Japan Precision Medicine Platform (JPP), a secure information sharing platform for medical data designed to improve medical data analysis and medical research domestically across Japan; FDA grants Fast Track Designation for Aspen Neurosciencce Parkinson's disease treatment; Genialis announces a new data-sharing collaboration with Cancer Research Horizons to better predict responses to KRAS inhibitors, immunotherapies, and other emerging classes of therapeutics; and more.

    Oct 26, 2023

  • Follow the Money: Generative AI, bioMérieux Expands Oxford Nanopore Investment, Radiopharmaceuticals Development, More

    Bio-IT World | bioMérieux further invests in Oxford Nanopore’s in vitro diagnostics; Automata Technologies raises funds for lab automation; NVIDIA and others invest in Iambic Therapeutics (formerly Entos) for generative AI; and more.

    Oct 25, 2023

  • A Shift Toward Multiomics: How Genome Sequencing is Improving Human Health

    Bio-IT World| There has perhaps never been a more exciting time to work in genetics. Thanks to technological advances and information sharing through various industry and academic collaborations, we know more today about the human genome and how it influences human health than could have ever been previously imagined.

    Oct 20, 2023

  • Multi-Lab Preclinical Model Aims To Solve The Reproducibility Crisis

    Bio-IT World| A new preclinical system put to the test by a network of labs to adaptively study a handful of stroke treatments has succeeded in demonstrating that high-quality science is “feasible, practical, and less expensive than doing things the wrong way.”

    Oct 18, 2023

  • Illumina Ordered To Unwind Acquisition Of GRAIL

    Bio-IT World| The European Commission (EC), under the EU Merger Regulation (EUMR), released a statement last week announcing it has taken restorative measures that require Illumina to unwind its acquisition of GRAIL. The acquisition was completed before the EC provided approval, breaching EU merger control rules.

    Oct 16, 2023

  • Navigating the Data-Rich Landscape of Healthcare: The Utility of Data Exploration and Visualization

    Bio-IT World| In the ever-expanding universe of real world data, exploration and visualization strategies have become indispensable. This article presents 5 takeaways relevant to these strategies.

    Oct 13, 2023

  • Low-Bass Music Controls Insulin Release From Designer Cells

    Bio-IT World| Scientists in Switzerland have figured out how to remotely control genes in a way that could one day enable diabetics to produce and administer insulin directly in their body rather than relying on injections, inhalers, and pumps. Low-bass heavy popular music and movie soundtracks are being used to trigger insulin release from designer cells in implantable capsules when intentionally directed at the implant site.

    Oct 11, 2023

  • Proteomics Enables Vastly Improved Cardiovascular Disease Prediction

    Bio-IT World| The rise and fall of blood protein levels over time is an astonishingly good way to assess the risk of major atherosclerotic cardiovascular disease (ASCVD) events such as myocardial infarction (heart attack), as well as an ideal biomarker of the progression of disease and its regression in response to treatment.

    Oct 10, 2023

  • Children’s Mercy Brings Long Read Sequencing to Clinical Care

    Bio-IT World Beginning today, the research team at Children’s Mercy Kansas City is bringing long read sequencing to clinical care, following three years of research and testing of PacBio HiFi sequencing. The transition is expected to speed the diagnostics odyssey for critically ill patients and their families.

    Oct 6, 2023

  • Synthace’s ‘Design of Experiments’ Approach Enables Multi-Factorial Wet Lab Experiments

    Bio-IT World| INNOVATIVE PRACTICES AWARDS—Cultured meat may not be the standard use case for a Bio-IT World Innovative Practices Award, but the entry from Higher Steaks and Synthace caught the judges’ attention less for its application as for the innovation in experimental design.

    Oct 4, 2023

  • Bio-IT World Issues 2024 Innovative Practices Awards Call for Entries

    Bio-IT World| Bio-IT World is accepting entries for the 2024 Innovative Practices Awards, a competition designed to recognize the most exciting partnerships and projects pushing the life sciences industry forward.

    Oct 3, 2023

  • Chan Zuckerberg Life Sciences Computing System, Microsoft and Paige AI Partnership, Rehm Takes Chair of GA4GH

    Bio-IT World| Paige and Microsoft aim to build the world’s largest image-based AI models for digital pathology and oncology; Flatiron Health and FDA partner; HHS extends partnership with Regeneron; the GA4GH Board of Directors has elected Heidi Rehm to succeed Ewan Birney; and more.

    Sep 28, 2023

  • Follow the Money: NIH Establishes “Multi-Omics” Data Research Center, Huge Funding for Advancing AI Platform

    Bio-IT World| Moderna and Immatics launch a strategic research and development collaboration to pioneer novel and transformative therapies for cancer patients with high unmet medical need; The National Institutes of Health is establishing the Multi-Omics for Health and Disease Consortium to advance the generation and analysis of “multi-omic” data for human health research; Generate:Biomedicines has secured huge funding to advance its AI platform used to increase precision, speed, and probability of success of novel therapeutics; more.

    Sep 27, 2023

  • The Why, How, and Hope of Generative AI and Data Technology With Bryn Roberts

    Bio-IT World| As artificial intelligence continues to rapidly develop, it is tempting for organizations to rush into using AI—or at least an AI buzzword. In the latest episode of the Trends from the Trenches podcast, host Stan Gloss channels Simon Sinek and challenges Bryn Roberts to start with why.

    Sep 26, 2023