• No Cytokine Storm, ‘Bursty’ Disease Spread: Biomarkers For Elevated Risk: COVID-19 Updates

    Bio-IT World  | Japanese researchers argue there is no cytokine storm, computer-designed protective proteins, ELISA test for antibodies, COVID-19’s impact on Black and Hispanic communities, a “burstier” model of disease spread, and new biomarkers for elevated risk. Plus, the International Vaccine Institute preps with Gates money, 3M funds vaccine researcher, and more.

    Sep 10, 2020

  • Beyond the Rule of 5: Vastly Expanding Targetable Drugs

    Bio-IT World | At the Drug Discovery Chemistry Virtual conference, researchers from industry and academia provide a glimpse into the expanse of pharmaceuticals available beyond Lipinski’s Rule of 5, an endeavor that will hopefully enable the development of much more specific agents with vastly expanded targetable options.

    Sep 8, 2020

  • Computational Tool Could Improve Clinical Success Rate Of Drugs

    Bio-IT World  A newly developed translatable components regression (TransComp-R) model, developed by researchers from Purdue University and the Massachusetts Institute of Technology (MIT), recently identified an overlooked biological mechanism possibly responsible for resistance to the drug infliximab commonly prescribed to patients with inflammatory bowel disease (IBD).

    Sep 8, 2020

  • Mouse Models, Machine Learning, Triggering Proteins: COVID-19 Updates

    Bio-IT World   A potential new screening approach, improving immune response to vaccines, new mouse models of SARS-CoV-2, exploring ACE2 receptor activity, a protein that may trigger blood clots, the importance of placenta tissue, hopeful signs that a single vaccine can do the job, and a bioengineering technique to boost production of proteins that prompt antibody development. Plus, machine learning to help identify drug combinations that can be repurposed as potential therapies.

    Sep 3, 2020

  • Phil Baran on the Quest to Make Chemistry Boring Again

    Bio-IT World | Phil Baran of Scripps Research is dedicated to simplifying chemical synthesis, not to create techniques that are “gimmicky” but will instead become the standard processes of the future. Maybe, “fifty years from now,” he predicts, “we’ll look back in curiosity at chemists of our age who had stages in their syntheses instead of making everything in 1-3 steps.”

    Sep 2, 2020

  • Truth Challenge v2: Latest Challenge Results From Genome In A Bottle

    Bio-IT World  PrecisionFDA and The Genome in a Bottle (GIAB) consortium have announced the results of the Truth Challenge V2: Calling Variants from Short and Long Reads in Difficult-to-Map Regions such as segmental duplications, and the Major Histocompatibility Complex (MHC).

    Sep 2, 2020

  • A Virtual Feast: A Preview of Bio-IT World 2020

    Bio-IT World | The 2020 Bio-IT World Conference & Expo Virtual includes three days full of content, networking, and interaction across 16 tracks, plenary session, workshops, posters, awards, and happy hours. And for the first time ever, many presentations will be available on demand after their first showing. We are already building our agenda.  

 

Sep 1, 2020

  • Racial Impacts of COVID-19, Neutralizing Antibodies, More

    Bio-IT World | Racial segregation of COVID-19 is following HIV patterns, more data on neutralizing antibodies, four months of data from Italy's use of hydroxychloroquine, and a computer model for school launches. Plus, an award from the UK government for vaccine development. 

    Aug 28, 2020

  • UK Biobank Contracts With DNAnexus, AWS to Build Data Analysis Platform

    Bio-IT World  UK Biobank, a long-term study of health data from 500,000 UK volunteers, announced today that it is developing its own cloud-based Data Analysis Platform to make its extensive medical data available to a broader range of researchers around the world. Funding for the Data Analysis Platform has come from Wellcome, and it will be developed over the next three years by DNAnexus in collaboration with Amazon Web Services (AWS).

    Aug 26, 2020

  • Vertiv, Pure Storage, And More: News From August 2020

    Bio-IT World   August featured exciting new, products, and partnerships from around the bio-IT community from innovating companies, organizations, and universities, including Vertiv, Pure Storage, and more.

    Aug 25, 2020

  • Beetle Viruses, Nitrate Supplements, Missing Sense of Smell: COVID-19 Updates

    Bio-IT World | How a beetle virus is informing SARS-CoV-2 research, plus nitrate supplementation for aid breathing, new small molecules active against the virus, and a theory for why COVID-19 patients lose their sense of smell. Plus, $9.8 million from DOD for vaccine research and virus-like particles for vaccine development.

    Aug 21, 2020

  • Combined Monogenic, Polygenic Risk Scores Could Change Medical Understanding of Disease

    Bio-IT World | In a paper published today in Nature Communications, IBM and the Broad Institute reported the first results of their collaboration to develop predictive models for cardiovascular disease.

    Aug 20, 2020

  • Bringing Peer Review To Early COVID-19 Research, More News

    Bio-IT World | New insights into the SARS-CoV-2 spike protein, a daily aerosol protectant, a look a death rates in 1918 and now, and a journal dedicated to publishing COVID-19 research with visible peer review. Plus new funding from NIH and the American Heart Association to enable further research on SARS-CoV-2 and COVID-19.

    Aug 18, 2020

  • Bringing Peer Review To Early COVID-19 Research, More

    Bio-IT World | New insights into the SARS-CoV-2 spike protein, a daily aerosol protectant, a look a death rates in 1918 and now, and a journal dedicated to publishing COVID-19 research with visible peer review. Plus new funding from NIH and the American Heart Association to enable further research on SARS-CoV-2 and COVID-19.

    Aug 14, 2020

  • Five Steps to Commercialization Success and Common Challenges You Can Easily Avoid

    Bio-IT World Contributed Commentary | It’s no surprise that advancements in novel technologies and the advent of big data have propelled significant breakthroughs in pharmaceutical development. The last decade has not only seen an increase in new chemical and biological entities but also significantly more innovative medicines reaching the market. Looking to the future, we also expect to see an intensified focus on neglected diseases as new and emerging biopharma companies (EBP) drive new medicine launches. However, to get there, organizations reaching for “first-in-market” status or securing key market areas depends on their ability to swiftly commercialize these new technologies and therapeutics.

    Aug 17, 2020

  • New Computational Tool from St. Jude Tackles ‘The Other 98%’ of Human Genome

    Bio-IT World | St. Jude Children's Research Hospital scientists have developed a computational tool to identify cancer-causing mutations lurking in the vast and largely unexplored regions of the human genome.

    Aug 13, 2020

  • NIH Launches Data Science for Health Discovery and Innovation in Africa Grant Program

    Bio-IT World In a virtual symposium this week—rescheduled from a live event in Uganda—the National Institutes of Health launched a new program: Harnessing Data Science for Health Discovery and Innovation in Africa (DS-I Africa). The program will leverage data science technologies and prior NIH investments to develop solutions to the continent’s most pressing public health problems through a robust ecosystem of new partners from academic, government, and private sectors.

    Aug 12, 2020

  • Learning the Language of Data Science and Pushing Science Forward

    Bio-IT World | In our current COVID-19 reality, the NIH’s Associate Director for Data Science sees an opportunity for a leap forward in our thinking about data sharing.

    Aug 11, 2020

  • Successful Data Migration Projects Take Planning

    Bio-IT World Contributed Commentary | Given all the merger and divestiture activity among companies, there will always be a need to move data from one system to another. Proper planning and user feedback are just a few ways to ensure a successful migration project.

    Aug 10, 2020

  • Researchers Using Models To Understand COVID-19, Other News

    Bio-IT World | Researchers are continuing to analyze COVID-19 through several models. A new mouse model is being developed in China to test and confirm the efficacy of a potential vaccine, while a researcher in the US is using computer models to understand the structure of the virus.

    Aug 7, 2020