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Inflammatory Clock Measures ‘Universal’ Hallmark Of Aging
Bio-IT World | Systemic chronic inflammation—a universally strong signal of ill health associated with all nine hallmarks of aging and diseases that collectively represent the leading causes of disability and mortality worldwide—can now be measured by an inflammatory clock of aging (iAge) developed by investigators at the Stanford University School of Medicine and the Buck Institute for Research on Aging. It is the first “actionable clock” that predicts multimorbidity, frailty, immunological health, and chronic diseases of aging.
Jul 15, 2021
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Strateos Makes Cloud Lab Software Available to In-House Labs
Bio-IT World | Strateos has launched its SmartLab Software which enables research organizations of any size to manage scientific workflows in-house while integrating automation with a modular, cloud-based software platform.
Jul 13, 2021
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Strep A Vaccine Development No Longer ‘A Bridge Too Far’
Bio-IT World | In at least two, placebo-controlled randomized trials getting underway in the next year, participants will be purposefully infected with a strain of group A streptococcus (Strep A) causing acute pharyngitis (strep throat) in a human challenge test of candidate vaccines intended to confer protection.
Jul 8, 2021
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Clonally-Derived Workflows: The Need For Wrap Around Data Packages For Regulatory Submissions
Bio-IT World | As part of regulatory submissions commercial labs are required to demonstrate that their clonal-derivation process is sound and that the high-value master cell submitted, did indeed, start from a single cell. Process validation (is the process fit for purpose?) and subsequent verification (is the process still fit for purpose?) becomes the backbone of clonal assurance.
Jul 7, 2021
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Implantable Pharmacy-On-a-Chip Now Under Fasttrack Development
Bio-IT World | A trio of universities are putting their heads together to engineer a wirelessly controlled bioelectronic implant intended to help soldiers adapt to new time zones or drastic changes in their work schedules by releasing peptide-based therapies to harmonize their central and peripheral circadian clocks.
Jul 6, 2021
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Follow the Money: AI-Powered Drug Discovery, Remote Access Labs
Bio-IT World | Insilico Medicine closes a Series C for AI-powered drug discovery, while other investments fuel remote access labs, natural products, high throughput screening, and more.
Jul 1, 2021
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The Value Of Lab Data Automation To Facilitate Data-Centric Research
Bio-IT World | In recent years, scientific research has moved from being process-driven to data-driven. Scientists are inferring the results of experiments by analyzing more data than ever, and it’s clear that companies that own the cleanest, best-annotated data will be the most successful in making ground-breaking discoveries within this paradigm. That said there are still significant challenges to data-driven research.
Jun 30, 2021
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Insilico Medicine Nets $225M, Pistoia Alliance Pushes Forward with FAIR, New Products
Bio-IT World | Colorado researchers publish a new method to increase the utility and equity of large genetic databases, new collaboration for BC Platforms and CareDuchenne, Minnesota Supercomputing Institute joins iRODS, and what’s next for Biogen and Eisai. Plus new products from Benchling, Egnyte, Cytek, Waters, Bruker, and more.
Jun 29, 2021
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Data Privacy Is Key to Enabling the Medical Community to Leverage Artificial Intelligence to Its Full Potential
Bio-IT World | If there’s anything the global pandemic has taught healthcare providers, it is the importance of timely and accurate data analysis and being ready to act on it. Yet these same organizations must move within the bounds of patient rights regulations, both existing and emerging, making it harder to access the data needed for building relevant artificial intelligence (AI) models. One way to get around this constraint is de-identify the data before curating it into one centralized location where it can be used for AI model training.
Jun 24, 2021
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Digital Patients Could Help More Drugs Reach Market
Bio-IT World | Clinical trials employing digital representations of patients and running in parallel with actual clinical trials could soon help researchers understand what separates responders and nonresponders to a drug.
Jun 22, 2021
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H3’s Data Centric Approach to Cancer Genomics
Bio-IT World | Lihua Yu took on the role of President of H3 three years ago; she oversees R&D and corporate development operations. She discusses her career trajectory and how the ideas and technologies fueling precision medicine have evolved since she joined H3.
Jun 22, 2021
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Snthesis Launches with Data Harmonization Lessons Learned From the Web
Bio-IT World | As the life sciences industry seeks to manage—and fruitfully mine—more and more data, data harmonization is a bit of a nagging thorn. Snthesis launched this year, applying lessons learned from the Semantic Web to knowledge graphs for life sciences.
Jun 17, 2021
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Molecular Tweezers Found To Attack Antibiotic-Resistant Bacteria
Bio-IT World | An international team of researchers has come up with a new application for “molecular tweezers” originally developed to untangle the amyloid nanofibers found in the brain of patients with Alzheimer’s and Parkinson’s disease. As it turns out, the tiny synthetic molecules may also be a way to prevent and treat bacterial infections like Staphylococcus aureus that have grown resistant to antibiotics
Jun 16, 2021
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Gamifying Vision: How Mobile Gaming Is Tracking Vision Degradation in Patients
Bio-IT World | Tilak Healthcare aims to combine video games with medical expertise so that the same vision monitoring tools that are reliable and useful for doctors will be playful and fun for users. If Tilak can achieve that, the company tools will be “sticky” enough to have a longstanding impact on the healthcare process for patients.
Jun 15, 2021
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DNA Data Storage Alliance Makes Its Case in New White Paper, Website
Bio-IT World | The DNA Data Storage Alliance, an organization formed last year by Twist Bioscience Corporation, Illumina, and Western Digital together with Microsoft Research, has launched its website and released its first white paper, an introduction to DNA data storage, endorsed by 29 member organizations.
Jun 10, 2021
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Achieving AI: Pharma’s Digital Transformation Pathway
Bio-IT World | What does it mean for a pharmaceutical company to be digital and how do we get there? That’s what Reza Olfati-Saber, PhD, Global Head AI & Deep Analytics, Digital & Data Science R&D, at Sanofi tackled yesterday at the DECODE: AI for Pharmaceuticals forum.
Jun 10, 2021
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Biology’s Role As A Driver of the Future of Computation Development
Bio-IT World | At the DECODE: AI for Pharmaceuticals forum yesterday, Puneet Batra, director of machine learning at the Broad Institute, outlined the mission of the new Eric and Wendy Schmidt Center at the Broad: to position biology to drive the next era of computing.
Jun 9, 2021
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Biotechs, Pharma Talk Cloud at AWS Symposium
Bio-IT World | At the AWS Healthcare and Life Sciences symposium last week, several biotech, pharma, and genomics organizations presented their cloud-enabled workflows and highlighted how Amazon Web Services is enabling their research and efforts.
Jun 8, 2021
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Data Vision: How Pharma’s View of Data is Changing Healthcare
Bio-IT World | Kicking off the DECODE: AI for Pharmaceuticals forum held virtually this week, speakers from big pharma discussed the cultural challenges required to become a data-driven business and how doing so might position us for the next horizon in personalized medicine.
Jun 8, 2021
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New Fund for Early-Stage Life Sciences, Microscopy for Protein Dynamics: Follow the Money
Bio-IT World | AI for gene therapy, gastrointestinal disease, and other indications, VAST Data’s disaggregation of hardware and software, targeting transcription factors as druggable regions, a new approach to sharing computational research, and more.
Jun 3, 2021