• Big Data vs. Alzheimer’s

    Bio-IT World | Sudeshna Das directs the data core of the Massachusetts Alzheimer’s Disease Research Center (MADRC). She recently sat down with BioTeam to discuss how MGH is collecting and working with enormous datasets to push back against Alzheimer’s.

    Dec 21, 2021

  • Recursion, Roche-Genentech, Bayer Launch Multi-Million Dollar Collaborations

    Bio-IT World | Last week, Recursion announced two collaborations: a new collaboration with Roche and Genentech to leverage technology-enabled drug discovery through the Recursion Operating System (OS), and an expansion of an existing Bayer collaboration focused on inferential search.

    Dec 16, 2021

  • Nautilus Biotechnology Taking Protein Analysis To The Single-Molecule Level

    Bio-IT World | A growing number of companies are endeavoring to replicate the success of gene sequencing juggernaut Illumina in the burgeoning field of proteomics. A top contender is Nautilus Biotechnology, which has spent the past few years drumming up excitement about the potential for comprehensively profiled proteins to make therapeutic and diagnostic development more effective and time efficient.

    Dec 15, 2021

  • Seven Bridges Launches the Unified Patient Network With Genomic, EHR Data

    Bio-IT World | Seven Bridges Genomics has launched a new subsidiary, the Unified Patient Network (UPN), to facilitate clinical research and collaboration between participating health systems and biopharma companies. The UPN will combine de-identified sequencing data and EHR content for five million patients and allow biopharma companies to license cohorts from that dataset for research. Licensing fees from biopharma will fund the network.

    Dec 14, 2021

  • Why Mass Spectrometry Is Taking Over Affinity-based Approaches In Plasma Proteomics

    Bio-IT World | The demand for proteomics studies has increased in recent years, with growing emphasis on datasets capturing vast amounts of proteomics data from large cohorts of patients, with thousands of proteins measured in each person. In part, this has been led by developments in computational methods, like deep learning to analyze data, as well as advancements in sample analytical methodologies.

    Dec 10, 2021

  • Harvard and MIT Researchers Pursue Improved RNA and Cellular Therapies with eToehold Technology

    Bio-IT World | A group of cell engineers and synthetic biologists at Harvard University and Massachusetts Institute of Technology (MIT) has developed a tech tool called “eToeholds” that could help improve the safety and efficacy of RNA and cell therapies, in addition to enabling new forms of detection.

    Dec 9, 2021

  • Cupping Technique Has Standout Performance In DNA Vaccine Studies

    Bio-IT World | The ultimate challenge of drug delivery—successfully getting a medicine into a cell—has several lines of pursuit when it comes to nucleic acid-based vaccines and the latest and greatest is an ancient cupping technique which, at least in rodents, is almost unfathomably good at driving immune responses. To say the Rutgers University research team was surprised by the finding would be an understatement.

    Dec 8, 2021

  • Clive Brown on Field Biopsies, New Chemistry, Short Reads

    Bio-IT World | At Oxford Nanopore’s virtual Community Meeting this week, CTO Clive Brown presented new chemistries, previewed the Apple iPad Pro-powered Mk1D with an integrated MinION, teased the diagnostic capacities of “outy” sequencing, unveiled a browser base caller, and more.

    Dec 3, 2021

  • Follow the Money: Cloud R&D, Generative Biology, Robotics

    Bio-IT World | Platforms for machine-learning generative biology and cloud R&D, drug delivery chip for therapies at the tumor site, and AI-driven drug discovery and robotics.

    Dec 2, 2021

  • Cloud Hygiene and Cost Optimization at Johnson & Johnson

    Bio-IT World | TRENDS FROM THE TRENCHES—Tom Messina has worked in various roles for Johnson & Johnson dating back to 1999 and is currently an IT Director in J&J’s Pharmaceutical R&D division, Janssen. BioTeam had a chance to speak with Tom recently to appreciate how J&J is leveraging cloud compute and storage resources to maximize innovation and growth while controlling costs.

    Dec 1, 2021

  • Gilead Chooses AWS, Illumina, Sequoia Fund Chinese Startups, More

    Bio-IT World | Illumina powers the Canadian COVID-19 Genomics Network, organ-on-a-chip explores infectious disease, and cell analysis acquisitions. Plus new products from PerkinElmer, Bio-Rad, Roswell Biotechnologies, Genialis, and more.

    Nov 30, 2021

  • Building the Data Foundation for Faster Time to Science in Healthcare

    Bio-IT World | Genomics and artificial intelligence (AI) are key to this quest and at-scale advancement of personalized medicine. Both, however, require liquid data and modern data infrastructure that re-imagines the role of data and how it is used.

    Nov 23, 2021

  • Gut Microbiome Linked To Aggressive Prostate Cancer

    Bio-IT World | Evidence has been mounting for decades that what men eat can lower or raise their risk of prostate cancer—including aggressive forms of the disease that can be lethal. But that’s only part of the story.

    Nov 22, 2021

  • Biopharma’s Dark Data Problem

    Bio-IT World | Worldwide spending on pharmaceutical R&D will reach $230 billion by 2026. So with investment dollars flowing in and R&D continuing an upward trajectory all should be well, right? Well… not exactly. Like many industries, pharmaceutical companies are facing a data problem—a dark data problem.

    Nov 19, 2021

  • Recursion’s Vision for the New Shape of Drug Discovery

    Bio-IT World | As a “digital native,” Recursion is working to reshape the drug discovery industry—quite literally. Gone is the vision of a traditional discovery funnel, wide at the top and slowly narrowing. Instead, Recursion proposes a drug discovery machine powering a T-shaped funnel where many options are considered, but failure is fast and the candidates that advance have a potentially higher likelihood of being a successful treatment. Easier said than done.

    Nov 17, 2021

  • Unique Repurposing Approach Identifies Potential Alzheimer’s Disease Drug

    Bio-IT World | Trials for Alzheimer’s disease (AD) drugs have repeatedly failed with billions of dollars invested. But a new, multidisciplinary drug repurposing model, described in a recent article in Nature Aging, combines drug repurposing with precision medicine, network-based drug targeting, induced pluripotent stem cell (iPSC) technology, and real-world data analysis.

    Nov 16, 2021

  • MemVerge’s Vision for Big Memory Computing

    Bio-IT World | The vision, Charles Fan explains, is big memory. Fan and two other co-founders launched MemVerge, an all-memory storage start-up that Fan calls quite disruptive and high risk—but also the compute architecture of the future.

    Nov 11, 2021

  • What’s Behind Growing Adoption Of Cell-Based Vaccine Platforms

    Bio-IT World | Cell-based vaccines, initially developed to add speed and scale to pandemic response efforts and reduce dependency on chickens in the vaccine manufacturing process, have over the past few years also shown to be more reliably effective than traditional, egg-based products.

    Nov 10, 2021

  • NVIDIA GTC: Networking, Healthcare AI, Modeling and Simulation

    Bio-IT World | At the NVIDIA GTC event, wide ranging announcements covered new networking capabilities, new AI capabilities, and new tools to advance healthcare and life sciences research.

    Nov 9, 2021

  • Genetic Sequencing Will Enable Us To Win The Global Battle Against COVID-19

    Bio-IT World | Using genetic sequencing to identify pathogens and respond to outbreaks is hardly new. The emergence of the SARS-CoV-2 in late 2019 was a game-changer, however. While SARS-CoV-2 was identified and sequenced in record time, it proved impossible to contain. It quickly became apparent that existing surveillance systems were not up to the task of tracking a fast-moving virus that spread asymptomatically. The speed and scale of Coronavirus spread provided a wake-up call highlighting our vulnerability to a global pandemic. But bioinformatics plays a crucial role.

    Nov 5, 2021