Creative Biostructure Enables Protein Secondary Structure Investigation with Various Services

Creative Biostructure, a biotechnology company specialized in providing services for scientists in the field of structural biology, now provides a series of services to help investigate protein secondary structure.

Proteins' secondary structure is made up of stretches or strands that have distinctive local structural conformations based on hydrogen bonding. α-helix and β-sheet are the two primary forms of protein secondary structures. The side chain of the amino acid sequence stretches laterally in the right-handed strand known as the α-helix. Protein structure stability is a result of hydrogen bonding. A β-sheet's hydrogen bond fits between the strands (inter-strand). The sheet conformation is composed of pairs of strands lying side by side. The carbonyl oxygens in one strand interact with the amino hydrogens of the adjacent strand.

For the investigation of protein secondary structure, Creative Biostructure offers a number of services. It has been used to better understand the higher-order structure (HOS) product quality attributes of the protein under study and to support stability studies, formulation development, process development, and comparability studies by quantifying the secondary structure components such as α-helix, β-sheet, bends, and turns.

At present, Creative Biostructure mainly provides the following secondary structure analysis services:

Circular Dichroism (CD) Spectroscopy Service

In structural biology, CD spectroscopy is a method that is frequently used to investigate the secondary structure, tertiary structure, conformational changes, as well as folding and binding interactions involving protein molecules.

Fourier Transform Infrared (FTIR) Spectroscopy Service

As part of the HOS characterization, FTIR spectroscopy has been used to determine the secondary structure of the targeted protein.

“We believe that we are uniquely positioned to leverage our deep expertise in structural biology to address the growing demand for the analysis of protein secondary structure.” Said Joanna, the chief marketing staff at Creative Biostructure.

Please visit https://www.creative-biostructure.com/secondary-structure-analysis.htm to know detailed information about the secondary structure analysis service provided by Creative Biostructure.