MicrobioSeq Division Releases Microbial Single-Cell Genome Sequencing to Reveal Heterogeneity of Microbial Populations

MicrobioSeq represents the microbial genomics division of CD Genomics headquartered in New York, USA. CD Genomics is a genomics service company with good reputation in providing reliable de novo sequencing, genotyping, microarray, and bioinformatics services. With years of experience in the pharmaceutical and life science sector, CD Genomics recently announced microbial single-cell genome sequencing to reveal the heterogeneity of microbial populations.

The latest advances in technology based on single-cell sequencing have allowed us to decipher the genetic code and genomic variation of uncultured microorganisms. Traditional 16S/18S/ITS sequencing and metagenomics have limited functions because they can only provide average results and ignore outliers. CD Genomics MicrobioSeq provides microbial single-cell genome sequencing to reveal the heterogeneity of microbial populations. Single-virus genome sequencing can also be used to answer biological questions about viral mmunities.

“Single-cell sequencing methods have led to a huge shift in the field of microbial genomics, from microbial population analysis to comprehensive research on individual microorganisms. We provide single-cell genome sequencing to decipher the diversity of microorganisms. The workflow of this service generally includes single-cell preparation, cell lysis, single-cell genome amplification, library construction and whole-genome sequencing. Depending on the type of samples, we utilize advanced flow-assisted cell sorting (FACS), laser-capture-microdissection, micromanipulation or microfluidic platform to perform single-cell isolation. The isolated cells are subsequently lysed and each genome is amplified through whole-genome amplification (WGA) methods (multiple-displacement-amplification (MDA) or MALBAC). After WGA, the amplified DNA is used to create libraries for Illumina sequencing. ” said the chief scientist of CD Genomics.

In addition to the above, CD Genomics also provide single-virus genome sequencing to study the diversity of viruses and the evolution of viral genomes. Coupled with microbials ingle-cell genome sequencing and single-virus genome sequencing,CD Genomics can help you discover discover low-abundance microbial members, reveal phylogenetic relationships, infer microbial evolution, and explore potential biosynthetic/metabolic processes. It has been widely used in scientific research, epidemiology, human health and drug development and other fields.

What are the advantages of choosing CD Genomics’s solutions?

1. Standardized laboratory methods and quality assurance processes.
2. The most advanced microbial single-cell sequencing technologies and bioinformatics tools.
3. Streamlined single-cell sorting and lysis, whole genome amplification, barcoded library generation and multiplexing sequencing.

About MicrobioSeq Divison of CD Genomics

MicrobioSeq is the microbial genomics division of CD Genomic, which is a genomics service company with a good reputation for providing reliable microbial sampling products, microbial testing services, microbial genomics services, and integrated bioinformatics services.