Synthego Offers Free CRISPR Design Tool

By Bio-IT World Staff 

May 16, 2017 | Synthego today announced new online CRISPR tools that make accessible over 100,000 genomes for free, fast, and easy world-class target design. Consisting of a guide designer and a design validator, Synthego’s software addresses gaps in the CRISPR design process, and allows both sophisticated and novice researchers to reduce the time it takes to create optimal designs from hours to minutes.

The new CRISPR design tool lets researchers select a desired gene of interest from a curated list of more than 100,000 genomes, compared to the less than 100 provided by previous tools. Several built-in algorithms then instantly generate guide designs and recommendations for the most efficient targets with low off-target effects and highest likelihood to knock out the function of a gene. Finally, the user experience, which complements the tool’s power, has straightforward workflows for both advanced researchers as well as the first-time CRISPR users.

Additional features of the new Synthego software include the ability to seamlessly validate, share, and purchase synthetic single guide (sgRNA) design targets. Guides designed using other tools can be validated with Synthego’s tools to leverage its built-in algorithms and check for optimal target choice. Furthermore, Synthego’s tools enable easy sharing with peers using the simple yet unique feature of direct links to results. Finally, when a researcher is ready to begin their CRISPR experimental workflow, purchasing high efficiency synthetic sgRNA is a streamlined process in the Synthego software.

The new Synthego CRISPR tools are free to use and available at http://design.synthego.com.