Cloud Pharmaceuticals Enters R&D Agreement with Myos Corporation to Develop Small Molecules Targeting Sarcopenia and Cachexia
RESEARCH TRIANGLE PARK, NC, UNITED STATES - Jul 17, 2014 - Cloud Pharmaceuticals, Inc., a therapeutics company focused on cloud-based drug design and development, has entered an R&D agreement with MYOS Corporation (MYOS or the Company) (NASDAQ: MYOS), an emerging biotherapeutics and bionutrition company focused on the discovery, development and commercialization of products that improve muscle health and performance.
The research and development program will focus on product candidates related to the inhibition of targets in the myostatin regulatory pathway as well as inflammatory mediators associated with sarcopenia and cachexia. Under the terms of the agreement MYOS will have proprietary rights to the design and structure of any small molecules developed for the muscle-health treatment market.
MYOS has engaged Cloud Pharmaceuticals, which creates new drugs and drug candidates and accelerates the development process by implementing new, innovative cloud computing technology, to initiate synthesis and design for small molecules relevant to Furin regulation and Janus Kinase 3 (JAK3) inhibition.
Furin is a prototypical proprotein convertase that processes latent precursor proteins into their biologically active forms. Furin convertase plays a central role in the processing of myostatin to its biologically active form and therefore is a potentially important target for development of a therapeutic candidate. JAK3 is a tyrosine kinase which functions in signal transduction and is thought to be a factor in complex biochemical pathways central to inflammation. Candidates created in this research relationship will be the Companys first small molecules under consideration for further development as a treatment for age-related loss of muscle mass or sarcopenia in addition to cachexia.
Robert C. Ashton, Jr., M.D., Chief Medical Officer at MYOS commented, This agreement underpins MYOS commitment to focus on the expansion of our biotherapeutics development pipeline in important therapeutic areas of unmet need. We are excited to move forward in earnest with our agreement with Cloud Pharmaceuticals and utilize their high-performance drug design platform based on novel cloud computing resources with the goal of optimizing and expediting our drug development program. Importantly, Cloud Pharmaceuticals unique technology has the ability to rapidly create and test novel molecules reducing both the time and cost of traditional drug development.
MYOS hopes to report on the initial target testing with Furin convertase by the end of 2015. Meanwhile MYOS will continue to assess and identify additional small molecule candidates for further design and evaluation within the Cloud Pharmaceuticals platform.
About MYOS Corporation
MYOS is a developmental stage biotherapeutics and bionutrition company focused on the discovery, development and commercialization of products that improve muscle health and function essential to the management of sarcopenia, cachexia and degenerative muscle diseases. For information visit www.myoscorp.com.
About Cloud Pharmaceuticals, Inc.
Cloud Pharmaceuticals is a leader in the computational design of new drugs and subsequent rapid, information-driven drug development. Cloud Pharmaceuticals accelerates the drug discovery and design process in a way that delivers tangible results and true value for its partners. For information visit www.cloudpharmaceuticals.com.
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