GenomeQuest and Ingenuity Announce NGS Partnership

By Bio-IT World Staff

January 6, 2011 | GenomeQuest and Ingenuity Systems have announced a partnership to support next-generation sequencing (NGS) workflows specifically targeted for personalized medicine research. The companies will integrate GenomeQuest’s Sequence Data Management (SDM) platform with Ingenuity’s IPA software enabling researchers to exchange gene information, perform interactive analysis, and create and test hypotheses across the domains of genome sequencing and biological pathways.
 
"By integrating SDM and IPA, researchers can take NGS experimental results and place them into known and predicted biological contexts that include biological processes, functions, diseases, pathways, compounds, and relationships. This creates a fast and efficient way for researchers to move from a list of genes, isoforms, or variants to high-value discovery outcomes like identifying novel disease-causing variants, prioritizing drug targets, and generating testable hypotheses,” said Doug Bassett, Ingenuity's CSO and CTO in a press release.

Richard Resnick, GenomeQuest's CEO commented, “The name of the game in personalized medicine research is to identify and validate targets for stratification.  With this integration, researchers can use multi-genome analysis and comparative datasets to enrich and contract their data to the most promising targets and then, armed with pathways analysis and biological process tools, validate and narrow these targets or generate new hypotheses.  Researchers can have high confidence in these contextual studies because they are leveraging the manually reviewed biological findings that Ingenuity curates from the peer-reviewed literature.”

The integration of SDM and IPA will be available in the GenomeQuest RNA-Seq and multi-genome analysis workflows.  The integration is built on the respective application platforms: the GenomeQuest three-level API which provides complete access to all functionality and data at the sequence engine, workflow, and user presentation levels; and the IPA Integration Module which provides direct links to all content and analysis capabilities within IPA.